ReviewNature reviews. Neuroscience2025
Ripple contributions to human memory: making the spiking content count.
Review in Nature reviews. Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Article
- Arousal state modulates human hippocampal ripples.bioRxiv : the preprint server for biology · 2026Article
- Hippocampal Ripples during Offline Periods Predict Human Motor Sequence Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Memories shape our sense of self and enable adaptive behaviour based on prior experiences, yet the neural mechanisms underlying memory formation and retrieval are not fully understood. Building on work in animal models and the unique opportunities afforded by intracranial recordings, a growing number of studies have focused on the contributions of awake ripples (transient neural oscillations 20-100 ms long in the 80-150 Hz range) to human memory. Here, we review the body of evidence linking awake ripples to human memory and highlight relevant insights as well as unresolved discrepancies between studies. On the basis of previous evidence from work in animals that ripples may provide a biomarker for bursts of underlying population spiking activity, we suggest that examining the underlying spike content of ripples may help clarify their role in human memory and resolve these discrepancies. Recent support for this notion comes from human studies that, similarly to the prior animal work, relate patterns of neuronal spiking activity to ripples. Thus, our ability to understand the role of ripples in human memory may benefit from fully understanding these spiking events.
Indexed as
Identifiers
40962945What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.