ArticleScientific reports2025
AI-assisted phenotyping in a zebrafish hypophosphatasia model enables early and precise detection of skeletal alterations.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Hypophosphatasia (HPP) is a rare genetic disorder mainly affecting bone and tooth mineralization in patients due to ALPL gene mutations. Understanding genotype-phenotype correlations in HPP remains challenging due to different severities and the disease's heterogeneity. To address this, we established a novel zebrafish animal model (alpl
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