Evidence map›Paper›PMID 40962825›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Lung ultrasound score and left ventricular eccentricity index in preterm infants with respiratory failure - a pilot study.

Jacob Kelner, Naveed Hussain, Henry Chicaiza, Shalin Parekh

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jacob KelnerDepartment of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA. jkelner@connecticutchildrens.org.ORCID http://orcid.org/0009-0009-7466-9771
Naveed HussainDepartment of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA.ORCID http://orcid.org/0000-0002-1809-5760
Henry ChicaizaDepartment of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA.
Shalin ParekhDepartment of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA.ORCID http://orcid.org/0000-0002-3746-1412

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the association between lung ultrasound score (LUS) and left ventricular eccentricity index at end-systole (LVEI-s) and end-diastole (LVEI-d) in preterm infants with respiratory failure. STUDY

designThis prospective pilot study included 38 ultrasounds on 20 premature infants with Transient Tachypnea of the Newborn (TTN) and Respiratory Distress Syndrome (RDS) requiring non-invasive ventilation at birth. LUS, LVEI-s, and LVEI-d were obtained daily for 72 h. Linear regression analysis was performed to determine correlation.

resultsLUS positively correlated with LVEI-s (r = 0.47, p = <0.01) and LVEI-d (r = 0.63, p = <0.01) during the 72-hour study period in the RDS group, but not the TTN group. Correlation increased over the first 24 h (LVEI-s: r = 0.69, p = <0.01; LVEI-d: r = 0.68, p = <0.01) in the RDS group.

conclusionAs LUS increases, both LVEI-s and LVEI-d demonstrate measurable changes in infants with RDS. This association may enhance precision in diagnostic stratification and optimizing fluid management in neonatal lung disease.

Indexed as

Heart VentriclesLungRespiratory Distress Syndrome, NewbornRespiratory InsufficiencyTransient Tachypnea of the NewbornFemaleHumansInfant, NewbornInfant, PrematureLinear ModelsMalePilot ProjectsProspective StudiesUltrasonography

Identifiers

PMID40962825

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.