Evidence map›Paper›PMID 40962802›Full record

ArticleNature communications2025

Naiavirus: an enveloped giant virus with a pleomorphic, flexible tail.

Matheus Rodrigues, Victória Queiroz, Thalita Arantes, Henrique Limborço, Bruna Neiva, Nidia Arias, Talita Machado, Matheus Barcelos, Juliana R Cortines, Otavio Henrique Thiemann and 11 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Why did some viruses evolve to be giants while others did not?Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Matheus Rodrigues *Universidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil.
Victória Queiroz *Universidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil.
Thalita ArantesUniversidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil.
Henrique LimborçoUniversidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil.
Bruna NeivaUniversidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil.
Nidia AriasUniversidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil.
Talita MachadoUniversidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0002-6841-9874
Matheus BarcelosUniversidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil.
Juliana R CortinesUniversidade Federal do Rio de Janeiro, Departamento de Virologia, Instituto de Microbiologia Paulo de Góes, Rio de Janeiro, Brazil.
Otavio Henrique ThiemannUniversidade de São Paulo, Physics Institute of Sao Carlos, Trabalhador Sao Carlense Av., São Carlos, Brazil.ORCID http://orcid.org/0000-0001-9971-5863
Rafael Elias MarquesBrazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.ORCID http://orcid.org/0000-0002-6949-0947
Talita Diniz Melo-HanchukBrazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.ORCID http://orcid.org/0000-0001-7268-6687
Eliana Leonor Hurtado CelisSão Paulo State University (UNESP), Department of Genetic, Microbiology, and Immunology, Bioscience Institute and Institute of Biotechnology (IBTEC), Botucatu, Brazil.ORCID http://orcid.org/0000-0002-9546-1293
João Pessoa AraujoSão Paulo State University (UNESP), Department of Genetic, Microbiology, and Immunology, Bioscience Institute and Institute of Biotechnology (IBTEC), Botucatu, Brazil.ORCID http://orcid.org/0000-0002-9153-1485
Erik ReisUniversidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0001-5442-6240
Luiz Carlos Junior AlcantaraInstituto Rene Rachou, Fundação Oswaldo Cruz and Expanded Navigation for Intensive and Optimized Surveillance (NAVIO) Network, Belo Horizonte, Brazil.
Cezar Batista Cunha SantosSexto Distrito Naval da Marinha do Brasil, Ladario, Mato Grosso do Sul, Brazil.
Abdeali JivajiDepartment of Biological Sciences, Virginia Tech, 926 West Campus Drive, Blacksburg, VA, USA.
Rodrigo A L RodriguesUniversidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0001-7148-4012
Frank O AylwardDepartment of Biological Sciences, Virginia Tech, 926 West Campus Drive, Blacksburg, VA, USA. faylward@vt.edu.ORCID http://orcid.org/0000-0002-1279-4050
Jônatas Santos AbrahãoUniversidade Federal de Minas Gerais, Departamento de Microbiologia / Centro de Microscopia, Av. Antônio Carlos 6627, Belo Horizonte, Brazil. jonatas.abrahao@gmail.com.ORCID http://orcid.org/0000-0001-9420-1791

Funding

University of Washington Arboviral Research Network (UWARN)U01AI151698 · NIAID · UNIVERSITY OF WASHINGTON · PI Michael Gale, PETER MACGARR RABINOWITZ · 2020 to 2026
$13.3M
Coevolutionary Dynamics and Gene Exchange Between Nucleo-Cytoplasmic Large DNA Viruses and EukaryotesR35GM147290 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Frank O'Neill Aylward · 2022 to 2026
$1.9M
NIAID NIH HHS U01 AI151698NIGMS NIH HHS R35 GM147290
6 · The paper itself

Abstract

Numerous studies have shown that viruses are present in a variety of environments on Earth, acting as drivers of biogeochemical cycles and powerful selective forces. Among them, giant viruses of amoebae have garnered attention from the scientific community due to their large particles and extensive genomes. Here, we describe the discovery of one of the largest tailed viruses in the known virosphere (averaging 1350 nm), named Naiavirus. This virus, isolated from a swamp biome in Brazil, has particles with a never-before-seen morphology and composition, and represents the first giant amoeba virus with an external envelope covering the capsid and extending over a flexible tail region. The Naiavirus genome, with nearly 1 million base pairs, reveals a unique set of genes, and does not resemble any other virus previously isolated so far.

Indexed as

AmoebaGiant VirusesBrazilCapsidGenome, ViralPhylogenyVirionWetlands

Identifiers

PMID40962802
PMCPMC12443978

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.