Evidence map›Paper›PMID 40962522›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

[Causal relationship between

Xiao-Yang Zhou, Mei Yan, Ying-Bin Yue, Hailigulli Nuriddin, Xue-Mei Wang, Yong-Feng Cheng, Chun-Can Wu, Yu Liu

Abstract readEnglish Abstract
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao-Yang ZhouDepartment of Internal Pediatrics, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Mei YanDepartment of Internal Pediatrics, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Ying-Bin YueDepartment of Internal Pediatrics, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Hailigulli NuriddinDepartment of Internal Pediatrics, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Xue-Mei WangDepartment of Internal Pediatrics, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Yong-Feng ChengDepartment of Internal Pediatrics, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Chun-Can WuDepartment of Internal Pediatrics, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Yu LiuDepartment of Internal Pediatrics, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the causal relationship between

methodsThe datasets from genome-wide association studies were used to select the single nucleotide polymorphism loci significantly associated with Hp infection as genetic instrumental variables. The MR analysis model was used to investigate the causal relationship between ITP and Hp infection. A retrospective analysis was conducted on the medical data of 316 children with newly diagnosed ITP at the First Affiliated Hospital of Xinjiang Medical University from January 2020 to December 2023. The children were followed up for 1 year, and a multivariate logistic regression analysis was used to investigate the risk factors for cITP.

resultsThe inverse variance weighted analysis revealed that Hp infection was significantly associated with an increased risk of ITP (

conclusionsHp infection is a risk factor for the onset of ITP and is an independent risk factor for cITP in children.

Indexed as

Helicobacter InfectionsHelicobacter pyloriPurpura, Thrombocytopenic, IdiopathicAdolescentChildChild, PreschoolFemaleHumansInfantLogistic ModelsMalePolymorphism, Single NucleotidePrognosisRetrospective StudiesRisk FactorsChildClinical studyHelicobacter pyloriImmune thrombocytopeniaMendelian randomization

Identifiers

PMID40962522
PMCPMC12447942

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.