ArticleInternational journal of surgery case reports2025
Occult MALT lymphoma masquerading as benign cysts in Sjögren's syndrome: A case report of diagnostic dilemma.
Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSjögren's syndrome (SS) significantly elevates the risk of salivary gland lymphoma, primarily mucosa-associated lymphoid tissue (MALT) type, arising within chronic lymphoepithelial sialadenitis (LESA). Benign lymphoepithelial cysts (BLECs), common in SS, can radiologically mimic malignancy, posing diagnostic challenges when occult lymphoma develops. CASE PRESENTATION: A 53-year-old woman with established SS developed progressive bilateral parotid enlargement over years. Initial ultrasonography and CT imaging revealed bilateral septated cysts, ductal calculi, and heterogeneous gland architecture, interpreted as benign inflammatory disease or sialolithiasis. Subtotal parotidectomy performed for cosmetic concerns on the larger side yielded histopathology confirming MALT lymphoma arising within LESA and BLECs. DISCUSSION: This case underscores the diagnostic dilemma of cystic parotid lesions in SS, where benign-appearing BLECs can harbor or be adjacent to occult MALT lymphoma. The malignant transformation highlights the inherent risk within chronic LESA. Imaging features of BLECs and cystic lymphoma often overlap; key discriminators like restricted diffusion on MRI warrant attention. Fine-needle aspiration has limitations, necessitating histopathological evaluation of tissue for definitive diagnosis, especially with persistent gland enlargement.
conclusionPersistent or progressive parotid enlargement in SS, even with cystic features suggestive of benign disease, necessitates a high index of suspicion for occult lymphoma. Histopathological verification remains paramount for accurate diagnosis and timely intervention, emphasizing the critical need for integrated clinical, radiological, and pathological assessment in these high-risk patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.