Evidence map›Paper›PMID 40961235›Full record

ArticleMolecular biology of the cell2025

Robust CENP-A incorporation in human cells is independent of transcription and cohesin components.

Reito Watanabe, Carlos Perea-Resa, Michael D Blower

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular biology of the cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Identification of chromatin-associated RNAs at human centromeres.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Reito WatanabeDepartment of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118.
Carlos Perea-ResaCentro de Biología Molecular Severo Ochoa, Madrid 28049, Spain.
Michael D BlowerDepartment of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118.ORCID 0000-0002-5037-1972

Funding

Transcriptome regulation during mitosisR01GM122893 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI BLOWER, MICHAEL DEMIAN · 2017 to 2023
$2.0M
NIGMS NIH HHS R01 GM122893
6 · The paper itself

Abstract

Centromeres are essential chromosomal components that ensure proper cell division by serving as assembly sites for kinetochores, which connect chromosomes to spindle microtubules. Centromeres are marked by the evolutionarily conserved centromere-specific histone H3 variant, CENP-A, which is deposited into centromere nucleosomes during G

Indexed as

Cell Cycle ProteinsCentromere Protein AChromosomal Proteins, Non-HistoneAnimalsCentromereChromatinCohesinsDrosophila melanogasterDrosophila ProteinsHistonesHumansMitosisTranscription, GeneticCell Cycle ProteinsCENPA protein, humanCentromere Protein AChromatinChromosomal Proteins, Non-HistoneCohesinsDrosophila ProteinsHistones

Identifiers

PMID40961235
PMCPMC12562020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.