Evidence map›Paper›PMID 40961203›Full record

ArticleScience advances2025

Specific host-algae relationship, yet flexible bacterial microbiome, in diatom-bearing foraminifera.

Elsa B Girard, Laura Del Rio-Hortega, Andi M A Pratama, Sophie Volkenandt, Jan-Niklas Macher, Susanne Wilken, Willem Renema

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Systematic Review: Long-Read Sequencing in Algal Studies.International journal of molecular sciences · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elsa B GirardNaturalis Biodiversity Center, Darwinweg 2, 2333 CR Leiden, Netherlands.ORCID 0000-0001-5785-542X
Laura Del Rio-HortegaNaturalis Biodiversity Center, Darwinweg 2, 2333 CR Leiden, Netherlands.ORCID 0000-0002-9278-0539
Andi M A PratamaMarine Science Department, Faculty of Marine Science and Fisheries, Hasanuddin University, Jl. Perintis Kemerdekaan Km. 10 Tamalenrea, Makassar 90245, Indonesia.ORCID 0000-0002-3769-2245
Sophie VolkenandtNaturalis Biodiversity Center, Darwinweg 2, 2333 CR Leiden, Netherlands.
Jan-Niklas MacherNaturalis Biodiversity Center, Darwinweg 2, 2333 CR Leiden, Netherlands.
Susanne WilkenIBED, University of Amsterdam, Sciencepark 904, 1098 XH Amsterdam, Netherlands.ORCID 0000-0002-3852-557X
Willem RenemaNaturalis Biodiversity Center, Darwinweg 2, 2333 CR Leiden, Netherlands.ORCID 0000-0002-1627-5995

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whether the adaptive strategies of marine mixotrophs, organisms that combine heterotrophic and autotrophic nutrition, in response to global change are rooted in their symbiotic relationships is debated, especially for larger benthic foraminifera. Despite their importance in the ecosystem, there are controversial findings regarding the specificity of their algal endobionts, preventing a deeper understanding of their adaptive strategies. Using single-cell metabarcoding on 243 diatom-bearing foraminifera specimens from Indonesia, we found one highly dominant diatom strain in each foraminiferal host species bearing at least 90% of the reads in a majority of host species, whereas the bacterial community was very flexible, with only 25% of the variation explained by water depth, substrate type, location, and host species. Our results suggest that the adaptive strategy of the foraminiferal holobiont rather lies within its bacterial endobiome. Its dynamism likely facilitates the adaptive potential of foraminifera, supporting their proliferation across different environmental settings.

Indexed as

Aquatic OrganismsBacteriaForaminiferaDiatomsHost Microbial InteractionsIndonesiaOceans and Seas

Identifiers

PMID40961203
PMCPMC12442871

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.