Evidence map›Paper›PMID 40961149›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Aniruddha Tewary, Shreya Sengupta, Soumya Mukherjee, Nilanjana Hazra, Yon W Ebright, Richard H Ebright, Jayanta Mukhopadhyay

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Sticking around: σ factor dynamics and implications for transcription elongation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Aniruddha Tewary *Department of Chemical Science, Bose Institute, Kolkata 700091, India.ORCID 0009-0000-9682-4845
Shreya Sengupta *Department of Chemical Science, Bose Institute, Kolkata 700091, India.ORCID 0000-0002-7801-984X
Soumya MukherjeeDepartment of Chemical Science, Bose Institute, Kolkata 700091, India.ORCID 0000-0001-8739-0045
Nilanjana HazraDepartment of Chemical Science, Bose Institute, Kolkata 700091, India.ORCID 0009-0001-1569-7491
Yon W EbrightDepartment of Chemistry, Rutgers University, Piscataway, NJ 08854.ORCID 0000-0002-3835-3683
Richard H EbrightDepartment of Chemistry, Rutgers University, Piscataway, NJ 08854.ORCID 0000-0001-8915-7140
Jayanta MukhopadhyayDepartment of Chemical Science, Bose Institute, Kolkata 700091, India.ORCID 0000-0002-2948-5908

Funding

TRANSCRIPTION ACTIVATION BY CAPR01GM041376 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI RICHARD H. EBRIGHT · 1989 to 2026
$6.5M
BACTERIAL TRANSCRIPTION COMPLEXESR37GM041376 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI EBRIGHT, RICHARD H. · 2013 to 2022
$5.0M
DST | Science and Engineering Research Board (SERB) EMR/2017/002066DST | Science and Engineering Research Board (SERB) IPA/2020/000414HHS | NIH | Office of Extramural Research (OER) GM041376NIGMS NIH HHS R01 GM041376NIGMS NIH HHS R37 GM041376
6 · The paper itself

Abstract

A "σ cycle" in which the initiation factor σ associates with RNA polymerase (RNAP) core enzyme to permit transcription initiation and dissociates from RNAP core enzyme to permit transcription elongation, has been proposed to occur and to be an essential step for σ-exchange, with all principal σ factors from all bacteria. These proposals were based on studies of the principal σ factor of

Indexed as

Bacillus subtilisBacterial ProteinsEscherichia coliEscherichia coli ProteinsSigma FactorTranscription Elongation, GeneticTranscription, GeneticTranscription Initiation, GeneticDNA-Directed RNA PolymerasesGene Expression Regulation, BacterialMutationBacterial ProteinsDNA-Directed RNA PolymerasesEscherichia coli ProteinsRNA polymerase sigma 70Sigma FactorBacillus subtilisRNA polymerasesigma factorstranscription

Identifiers

PMID40961149
PMCPMC12478191

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.