ArticleJournal of hematopathology2025
A rare case of in situ follicular B-cell neoplasm involving sebaceous lymphadenoma.
Article in Journal of hematopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In situ follicular neoplasia (ISFN) is characterized by a monoclonal proliferation of BCL2-positive B cells harboring the translocation t(14;18)(q32;q21). These cells are confined to follicle centers and are usually identified incidentally, with a very low risk of progression to follicular lymphoma. Sebaceous lymphadenoma is a rare, benign salivary gland tumor, most commonly arising in the parotid gland, and is histologically defined by solid epithelial nests and cysts with sebaceous differentiation in a hyperplastic lymphoid stroma. We report an unusual case of ISFN arising within a sebaceous lymphadenoma. To the best of our knowledge, this association has not previously been reported.
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