ArticlePediatric surgery international2025
Postoperative complications following surgery for congenital hyperinsulinism and insulinomas in pediatric patients.
Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Somatostatin and Its Analogues as Second-Line Treatments in Non-Neoplastic Conditions.International journal of molecular sciences · 2026Review
- Single-center experience description of surgical management of diffuse congenital hyperinsulinism in a pediatric non-current cohort.Frontiers in endocrinology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo systematically describe postoperative complications in surgery for HI in pediatric patients.
methodsIn this retrospective single-center study, we systematically analyzed the rate and grade of complications according to the Comprehensive Complication Index (CCI), Clavien-Dindo Classification (CDC), and the Clavien-Madadi Classification (CMC) in 74 patients undergoing a total of 89 surgeries for CHI (N = 68) or pediatric insulinomas (N = 6) at Odense University Hospital, Denmark, from 01.01.2010 until 01.10.2024.
resultsPatients surgically treated for focal CHI had more favorable surgical outcomes with a mean CCI score of 10.8 vs. the diffuse CHI mean CCI of 26.3 (p = 0.0018). Surgical treatment for pediatric insulinomas resulted in a mean CCI of 28.9. In the total group, the most common complication was postoperative infection (29%), followed by delayed gastric emptying (20%). The rate of postoperative pancreatic fistula was 11%, but only 3.4% were clinically relevant. Eight percent of the surgical procedures resulted in complications classified as CMD grade IIIb or higher.
conclusionDespite the complex nature of surgery in pediatric patients with CHI or insulinomas, the majority had an uneventful recovery. Severe complications (CMC grade IIIb +) were, however, seen in 8%. Prospective, systematic postoperative complication score evaluation is encouraged in surgery for pediatric HI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.