Evidence map›Paper›PMID 40960543›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2025

Optimal Stent Expansion Indices for Predicting Outcomes in PCI of Calcified Coronary Lesions.

Eleni Ntantou, Alexandros A Siskos, William Camilleri, Martin Roos, Quinten Wolff, Thomas Kok, Isabella Kardys, Joost Daemen, Roberto Diletti, Jeroen M Wilschut and 3 more

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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Eleni NtantouDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Alexandros A SiskosDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
William CamilleriDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Martin RoosDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Quinten WolffDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Thomas KokDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Isabella KardysDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Joost DaemenDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Roberto DilettiDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Jeroen M WilschutDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Rutger-Jan NuisDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Nicolas M Van MieghemDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Wijnand K den DekkerDepartment of Cardiology, Cardiovascular Institute, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands. w.dendekker@erasmusmc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a lack of established stent expansion criteria to predict long-term outcomes following percutaneous coronary intervention (PCI) in calcified coronary lesions.

aimsThe aim of this study was to evaluate the relationship between various stent expansion indices and clinical outcomes including target lesion failure (TLF) following PCI in patients with calcified coronary lesions.

methodsThis study was a retrospective single-center study. Patients with native calcified coronary artery lesions treated with imaging guided PCI and the availability of final intravascular ultrasound or optical coherence tomography images were included. The association between eight stent expansion indices and long-term TLF was evaluated.

resultsA total of 280 lesions from 221 patients were analyzed. The median patient age was 71 years (Interquartile Range: 63-77), and 155 (70.1%) were male. Of the eight stent expansion indices, only the minimum stent area (MSA) > 100% of distal reference lumen area (HR 0.29; 95% CI 0.13-0.65; p = 0.003), MSA > 90% of distal reference area (HR 0.45; 95% CI 0.25-0.84; p = 0.012) and MSA > 5.0 mm

conclusionsIn the present retrospective analysis, a final MSA > 100% relative to the distal reference lumen area and MSA > 5.0 mm

Indexed as

Calcific coronary diseaseIntravascular ultrasoundIVUSMinimum stent areaMSAOCTOptical coherence tomographyPCIPercutaneous coronary intervention

Identifiers

PMID40960543

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.