ArticleEuropean archives of psychiatry and clinical neuroscience2026
Autism spectrum traits in adults with attention-deficit/hyperactivity disorder (ADHD): a hidden multifaceted phenotype marked by affective comorbidity, emotional dysregulation, and chronobiological disturbances.
Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Clinical Characterization of Emotional Dysregulation in Adults with and Without ADHD: A Cross-Sectional Multigroup Comparative Study.Brain sciences · 2026Article
- Sex differences in the response to treatment of attention deficit hyperactivity disorder.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
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11 authors.
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Abstract
backgroundAutism spectrum disorder (ASD) is a commonly observed comorbidity in children with attention-deficit/hyperactivity disorder (ADHD). Nevertheless, the impact of autism spectrum traits on clinical presentation and comorbidities in adults with ADHD remains largely underexplored.
methods105 adults with ADHD were recruited at the outpatient service of the Psychiatry Unit 2 at Pisa University Hospital and subdivided according to screening for ASD based on the Autism-Spectrum Quotient (AQ). Comparative analyses were performed for sociodemographic and clinical variables.
resultsParticipants with a positive screening for ASD (N = 23, 21.9%) were more frequently females, had a higher age at first clinical referral, higher comorbidity rates with mood and anxiety disorders, particularly social anxiety, and a lower rate of cannabis use disorder. They showed significantly greater severity of ADHD and emotional dysregulation, worse personality and interpersonal functioning, more depressive, cyclothymic and anxious temperamental dispositions, more pathological personality traits, increased biological rhythm disturbances and evening chronotype.
conclusionsAutism spectrum traits are commonly reported in adults with ADHD and may be associated with female sex and a complex clinical presentation characterized by affective comorbidity, more severe emotional dysregulation and chronobiological disturbances.
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