Evidence map›Paper›PMID 40960497›Full record

ArticleHistochemistry and cell biology2025

Increased Fos immunoreactivity in astrocytes in the raphe pallidus under hypoxia, not hypercapnia.

Kouki Kato, Risa Serizawa, Takuya Yokoyama, Nobuaki Nakamuta, Yoshio Yamamoto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Histochemistry and cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kouki KatoCenter for Laboratory Animal Science, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan.
Risa SerizawaLaboratory of Veterinary Anatomy and Cell Biology, School of Veterinary Medicine, Iwate University, 18-8, Ueda 3-Chome, Morioka, Iwate, 020-8550, Japan.
Takuya YokoyamaLaboratory of Veterinary Anatomy and Cell Biology, School of Veterinary Medicine, Iwate University, 18-8, Ueda 3-Chome, Morioka, Iwate, 020-8550, Japan.
Nobuaki NakamutaLaboratory of Veterinary Anatomy and Cell Biology, School of Veterinary Medicine, Iwate University, 18-8, Ueda 3-Chome, Morioka, Iwate, 020-8550, Japan.
Yoshio YamamotoLaboratory of Veterinary Anatomy and Cell Biology, School of Veterinary Medicine, Iwate University, 18-8, Ueda 3-Chome, Morioka, Iwate, 020-8550, Japan. yyoshio@iwate-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The raphe pallidus (RPa), a part of the caudal medullary raphe nucleus, has been suggested to participate in respiratory regulation. Therefore, hypoxia and hypercapnia are expected to affect the expression of Fos, a marker of cellular activation, in the RPa; however, there is currently no consensus on Fos expression in the RPa under hypoxic and hypercapnic conditions. The present study investigated the distribution of Fos expression in the RPa of rats exposed to hypoxia (10% O

Indexed as

AstrocytesHypercapniaHypoxiaProto-Oncogene Proteins c-fosRaphe NucleiAnimalsImmunohistochemistryMaleRatsRats, Sprague-DawleyRats, WistarProto-Oncogene Proteins c-fosAstrocytesFos immunoreactivityHypercapniaHypoxiaRaphe pallidusSerotonergic neurons

Identifiers

PMID40960497
PMCPMC12443861

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.