Evidence map›Paper›PMID 40960437›Full record

ArticleJACC. Case reports2025

Amplitude-Integrated/Continuous Electroencephalography for Early Detection of Low Cardiac Output After Chest Closure in an Infant.

Alessandro Barbaria, Mariarita Capizzi, Federica Sperandeo, Gloria Castelli, Giuseppe Isgrò, Tommaso Aloisio, Angela Satriano, Alessandro Giamberti, Massimo Mastrangelo, Marco Ranucci

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alessandro BarbariaDepartment of Cardiovascular Anesthesia and Intensive Care, I.R.C.C.S. Policlinico San Donato, Milan, Italy. Electronic address: alessandro.barbaria@grupposandonato.it.
Mariarita CapizziDepartment of Infant Neuropsychiatry, ARNAS Civico Di Cristina Benfratelli, Palermo, Italy.
Federica SperandeoDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Gloria CastelliDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Giuseppe IsgròDepartment of Pediatric Intensive Care Unit, I.R.C.C.S. Policlinico San Donato, Milan, Italy.
Tommaso AloisioDepartment of Cardiovascular Anesthesia and Intensive Care, I.R.C.C.S. Policlinico San Donato, Milan, Italy.
Angela SatrianoDepartment of Pediatric Intensive Care Unit, I.R.C.C.S. Policlinico San Donato, Milan, Italy.
Alessandro GiambertiDepartment of Pediatric and Adult Congenital Cardiac Surgery, I.R.C.C.S. Policlinico San Donato, Milan, Italy.
Massimo MastrangeloDepartment of Pediatric Intensive Care Unit, I.R.C.C.S. Policlinico San Donato, Milan, Italy.
Marco RanucciDepartment of Cardiovascular Anesthesia and Intensive Care, I.R.C.C.S. Policlinico San Donato, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWeaning from cardiopulmonary bypass in pediatric cardiac surgery is challenging, especially after prolonged procedures. Delayed chest closure may be necessary in cases of low cardiac output syndrome (LCOS) to support hemodynamic recovery. Although near-infrared spectroscopy is standard for neuromonitoring, amplitude-integrated electroencephalography (aEEG) and continuous electroencephalography (cEEG) are emerging tools. CASE SUMMARY: We report the case of a 6-month-old infant with transposition of the great arteries who required delayed chest closure after surgical repair. LCOS recurred after chest closure on postoperative day 3 despite stable near-infrared spectroscopy values. Retrospective aEEG/cEEG analysis, unintentionally initiated before closure, showed early EEG abnormalities preceding clinical signs, which were resolved after chest reopening. DISCUSSION: This case highlights the potential of aEEG/cEEG to detect early cerebral compromise due to LCOS, even when conventional monitoring appears normal, an association not well established in the literature. TAKE-HOME MESSAGE: Cerebral distress may be detected earlier with aEEG compared with standard monitoring, supporting timely LCOS identification and management.

Indexed as

acute heart failureatrial septal defectcongenital heart defectpediatric surgerytransposition of the great arteriesventricular septal defect

Identifiers

PMID40960437
PMCPMC12793864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.