ReviewInvestigative ophthalmology & visual science2025
IMI-Interventions for Controlling Myopia Onset and Progression 2025.
Review in Investigative ophthalmology & visual science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Safety and Efficacy of the D.D.C Dual-control Technology Spectacle Lenses in Delaying the Progression of Myopia: a Randomized Controlled Trial
A Pilot Evaluation of Refractive Error Progression in Pre-Myopic Children in Singapore With and Without Myopia Control Spectacles
Who cites it
48 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Biological mechanisms of atropine in myopia control (Review).Molecular medicine reports · 2026Pooled it
- Impact of exercise on myopia in children and adolescents and its modifying factors: a systematic review and meta-analysis.BMC pediatrics · 2026Pooled it
- Effects of table tennis on vision in children and adolescents: a multilevel dose-response meta-analysis.Frontiers in medicine · 2026Pooled it
- Defocus incorporated multiple segment spectacle lenses versus orthokeratology lenses for myopia control: a non-inferiority randomised clinical trial.BMC ophthalmology · 2026Trial
- Low concentration atropine eye drops and progression of myopia in children: multicentre placebo controlled, double masked, randomised trial in the UK (CHAMP-UK).BMJ (Clinical research ed.) · 2026Trial
- Effect of 0.01% Atropine on Choroidal Thickness and Ocular Growth in Pre-myopic Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Trial
- Stepwise Increase in Concentrations of Atropine Treatment for Myopia Control Study.Ophthalmology science · 2026Article
- Bioelectronic interfaces for restoring vision pathways.Materials today. Bio · 2026Review
- Progression with myopia control spectacles: identifying predictors of response to defocus incorporated multiple segment and highly aspherical lenslets spectacles in the French myopia cohort.BMJ open ophthalmology · 2026Article
- Three-year Comparative Efficacy and Safety of Repeated Low-level Red-light Therapy and Orthokeratology for Myopia Control in Children.Ophthalmology and therapy · 2026Article
- Low-Dose Atropine and Other Interventions for Pediatric Myopia: A Systematic Review and Bayesian Network Meta-analysis of Efficacy and Post-treatment Outcomes.Ophthalmology and therapy · 2026Review
- Two-Year Efficacy of Cylindrical Annular Refractive Elements Spectacle Lenses for Myopia Control in European Children.Ophthalmology science · 2026Article
- Validation of a Multimodal Wearable Device for Assessing Environmental and Behavioral Risk Factors of Myopia in Children and Adolescents.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Spectacle Lenses With Highly Aspherical Lenslets for Myopia Control: A Randomized Clinical Trial.JAMA ophthalmology · 2026Article
- Eight-Year Post-Trial Outcomes of a Two-Year Clinical Trial of DIMS Spectacle Lenses.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Distribution and Time Trends of Refractive Errors in Japanese Spectacle Wearers.Investigative ophthalmology & visual science · 2026Article
- Next-Generation Myopia Control Spectacles Hint at Defocus Opponency Circuits in the Retina.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Two-Year Changes in Astigmatism in Myopic Children Wearing Lenslet-ARray-Integrated Spectacle Lenses.Ophthalmology science · 2026Article
- Contemporary Research Questions in the Field of Contact Lenses and Where to Next?Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Review
- Association between pupil size and response to atropine therapy in the Atropine Treatment of Myopia study (ATOM2).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myopia is recognized as a significant public health problem, particularly in East and Southeast Asia. This has led to the development and evaluation of a range of interventions to slow its progression and delay its onset. Since the publication of the 2019 International Myopia Institute's review of interventions for controlling myopia onset and progression, treatment options have continued to grow in number. This article reviews the efficacy of such interventions under five categories: optical, pharmacological, environmental (behavioral), colored light, and surgical. In summarizing the efficacy of mature technologies, only randomized controlled trials were considered, although such data are very limited for emerging treatments. The overall conclusion is that there are multiple effective interventions in most categories. Further research should aim to understand the mechanisms underlying myopia progression and the modalities that slow its progression in order to develop more effective treatments.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.