Evidence map›Paper›PMID 40959855›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Bimetal-Phenolic Framework to Combat Bacterial Infections via Synergistic Biofilm Dispersal, Bacterial Killing and Immune Modulation.

Yaran Wang, Fan Wu, Lei Hua, Chang Gao, Siran Wang, Yong Liu, Yijin Ren, Linqi Shi, Henny C van der Mei, Yuanfeng Li

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yaran WangConsortium for Infection and Innovation (CII), Translational Medicine Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Fan WuConsortium for Infection and Innovation (CII), Translational Medicine Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Lei HuaConsortium for Infection and Innovation (CII), Translational Medicine Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Chang GaoConsortium for Infection and Innovation (CII), Translational Medicine Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Siran WangConsortium for Infection and Innovation (CII), Translational Medicine Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Yong LiuConsortium for Infection and Innovation (CII), Translational Medicine Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Yijin RenDepartment of Orthodontics, University of Groningen and University Medical Center Groningen, Groningen, 9700 RB, Netherlands.
Linqi ShiState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Functional Polymer Materials, Ministry of Education, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin, 300071, China.
Henny C van der MeiDepartment of Biomaterials & Biomedical Technology, University of Groningen and University Medical Center Groningen, Groningen, 9713 AV, Netherlands.ORCID https://orcid.org/0000-0003-0760-8900
Yuanfeng LiConsortium for Infection and Innovation (CII), Translational Medicine Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.

Funding

First Affiliated Hospital of Wenzhou Medical University 2025WMU-X001National Natural Science Foundation of China 22275043National Natural Science Foundation of China 22475156National Natural Science Foundation of China 52203184National Natural Science Foundation of China 52293383National Natural Science Foundation of China 52422307Wenzhou Municipal Science and Technology Major Project ZY2023031Zhejiang Clinovation Pride CXTD202501043Zhejiang Provincial Natural Science Foundation Outstanding Youth Project LR24H180001
6 · The paper itself

Abstract

The presence of drug resistance and extracellular matrix protection in biofilms makes it increasingly difficult to control bacterial infections using antibiotics. Therefore, there is an urgent need to develop new non-antibiotic approaches to eradicate drug-resistant bacterial infections. Here, a bimetal-phenolic framework (Que-Fe-CeMPF) is constructed by direct self-assembly of coordinated Fe

Indexed as

Anti-Bacterial AgentsBacterial InfectionsBiofilmsMetal-Organic FrameworksAnimalsHumansMicePseudomonas aeruginosaAnti-Bacterial AgentsMetal-Organic Frameworksanti‐inflammatorybiofilm degradationcatalytic activitylung infectionsmultifunctional nanomaterials

Identifiers

PMID40959855
PMCPMC12677615

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.