Evidence map›Paper›PMID 40959661›Full record

ArticleACS catalysis2024

Chemoselective Cu-Catalyzed Cross-Nucleophile Alkylarylation of Alkenes.

SangHyun Lee, Jianyang D Yu, Alex L Monterde, Sarah E Tung, Ya-Nong Wang, Brittany L Gay, Kami L Hull

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS catalysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Alkene Carboxy-Alkylation via COJournal of the American Chemical Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

SangHyun LeeUniversity of Texas at Austin, 100 East 24th Street, Austin, Texas, 78712, United States.ORCID 0000-0001-9519-137X
Jianyang D YuUniversity of Texas at Austin, 100 East 24th Street, Austin, Texas, 78712, United States.ORCID 0009-0001-6393-9395
Alex L MonterdeUniversity of Texas at Austin, 100 East 24th Street, Austin, Texas, 78712, United States.ORCID 0009-0001-6935-4312
Sarah E TungUniversity of Texas at Austin, 100 East 24th Street, Austin, Texas, 78712, United States.ORCID 0009-0009-6008-334X
Ya-Nong WangUniversity of Texas at Austin, 100 East 24th Street, Austin, Texas, 78712, United States.ORCID 0000-0002-5838-3855
Brittany L GayUniversity of Texas at Austin, 100 East 24th Street, Austin, Texas, 78712, United States.ORCID 0000-0002-6481-6071
Kami L HullDepartment of Chemistry, University of Texas at Austin, 100 East 24 Street, Austin, Texas, 78712, United States.ORCID 0000-0003-3102-2686

Funding

Transition Metal-Catalyzed Alkene FunctionalizationR35GM125029 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Kami Lee Hull · 2017 to 2026
$2.7M
NIGMS NIH HHS R35 GM125029
6 · The paper itself

Abstract

We report a general cross-nucleophile alkene alkylarylation which adds two different boronic acids, an alkyl and an aryl, across a vinylarene to afford 1,1-diarylalkanes. The excellent chemoselectivity derives from the distinct reactivities of the two boronic acids: the alkylboronic acid is selectively oxidized to an alkyl radical while the arylboronic acid favors transmetalation with the Cu(II)-catalyst. Mechanistic studies suggest that Lewis acid-Lewis base interactions between

Identifiers

PMID40959661
PMCPMC12435271

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.