Evidence map›Paper›PMID 40959588›Full record

ArticleInternational journal of general medicine2025

Influence of Prone Position on the Survival of COVID-19 Patients Undergoing Invasive Mechanical Ventilation: A Propensity Score Matching Study.

Yuwei Zheng, Chaochao Chen, Xiaojie Bi, Xiaowei Li, Jing Wang, Yufen Zheng, Yuan Yuan, Yongpo Jiang, Bo Shen, Yinghe Xu

Abstract read
In one paragraph

Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuwei Zheng *Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People's Republic of China.
Chaochao Chen *Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People's Republic of China.
Xiaojie Bi *Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People's Republic of China.
Xiaowei LiDepartment of Pathology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People's Republic of China.
Jing WangDepartment of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People's Republic of China.
Yufen ZhengDepartment of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People's Republic of China.
Yuan YuanDepartment of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People's Republic of China.
Yongpo JiangDepartment of Critical Care Medicine, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People's Republic of China.
Bo ShenDepartment of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People's Republic of China.ORCID 0000-0002-1662-3558
Yinghe XuDepartment of Critical Care Medicine, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The role of prone position (PP) in critically ill patients diagnosed with coronavirus disease 2019 (COVID-19) undergoing invasive mechanical ventilation remains unclear. This study aimed to evaluate the potential prognostic benefits of PP. Patients and methods: This retrospective study included data from 289 critically ill patients with COVID-19 who underwent invasive mechanical ventilation in a multicenter setting. Propensity score matching was used to match 156 patients (78 PP-treated, 78 non-PP-treated) after adjusting for age, sex, underlying disease, and Sequential Organ Failure Assessment score. Between-group comparisons of clinical data, laboratory results, and prognosis were performed. Kaplan-Meier (K-M) survival curve and univariate and multivariate Cox regression analyses were used to explore the relationship between PP and prognosis. Results: Prone positioning improved oxygenation (oxygenation index in the PP group increased consistently, with the greatest improvement observed on days 12-13 compared with the non-PP group [48 vs 32 mmHg; P < 0.001]) and increased hospital survival (80.8% vs 65.4%; P = 0.047). K-M survival curve analysis revealed that patients treated with PP had a more favorable prognosis (P = 0.025). Multivariate Cox regression revealed that PP was linked to lower risk of death (HR 0.389 [95% CI 0.173-0.878]), while age (HR 1.053 [95% CI 1.012-1.096]), Acute Physiology and Chronic Health Evaluation II score (HR 1.055 [95% CI 1.006-1.107]), and troponin T levels (HR 2.028 [95% CI 1.222-3.367]) were linked to higher risk of death in the overall survival of patients with COVID-19. Conclusion: PP improved oxygenation and increased the survival rate of critically ill patients with COVID-19 undergoing invasive mechanical ventilation. Adopting PP as much as possible during nursing care may enhance patient survival.

Indexed as

COVID-19mechanical ventilationprognosisprone positionsurvival

Identifiers

PMID40959588
PMCPMC12435498

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.