Evidence map›Paper›PMID 40959501›Full record

ArticleFrontiers in neurology2025

Association of low serum 25-hydroxyvitamin D levels with hearing loss severity in Meniere disease: a cross-sectional study.

Yunqin Wu, Zhenzhen Lai, Ange Li, Weiwei Han, Xiaoxia Liu, Weinv Fan

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yunqin Wu *Department of Neurology, Ningbo No. 2 Hospital, Ningbo, China.
Zhenzhen Lai *Department of Neurology, Tiantai People's Hospital of Zhejiang Provine, Tiantai Branch of Zhejiang Provincial People's Hospital, Hangzhou Medical College, Taizhou, Zhejiang, China.
Ange Li *School of Medicine, Shaoxing University, Shaoxing, China.
Weiwei HanDepartment of Rehabilitation, Ningbo No.2 Hospital, Ningbo, China.
Xiaoxia LiuDepartment of Neurology, Ningbo No. 2 Hospital, Ningbo, China.
Weinv FanDepartment of Neurology, Ningbo No. 2 Hospital, Ningbo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Growing evidence implicates vitamin D in inner ear homeostasis, though its association with Ménière's disease (MD) remains incompletely characterized. This study aimed to compare serum 25-hydroxyvitamin D (25(OH)D) levels between patients with MD and healthy controls and to assess its correlation with hearing thresholds in MD cohort. Methods: In this cross-sectional study, 49 patients with MD and 250 matched healthy controls were enrolled at our institution between January 2023 and January 2025. Groups were matched for demographics, comorbidities, exercise habits, and seasonal blood collection timing. Serum 25(OH)D levels and pure-tone audiometry (PTA) results were measured and analyzed. Results: Patients with MD exhibited significantly lower 25(OH)D levels than controls [18.4 ± 5.9 (45.9 ± 14.7 nmol/L) vs. 21.1 ± 6.2 ng/mL (52.7 ± 15.5 nmol/L); Conclusion: Hypovitaminosis D is associated with MD and hearing loss severity, warranting further longitudinal studies to explore causality and therapeutic implications.

Indexed as

hearing lossMeniere diseaseotolithic membranevitamin Dvitamin D deficiency

Identifiers

PMID40959501
PMCPMC12434304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.