ArticleInternational journal of reproductive biomedicine2025
Association of sperm protamine1 and protamine2 transcript content with paternal age: A cross-sectional study.
Article in International journal of reproductive biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Over the last decade, there has been a significant increase in average paternal age. Objective: The present study investigated the effects of male age on sperm parameters, DNA fragmentation, andprotamine1 ( Materials and Methods: In this cross-sectional study, 106 semen samples from normozoospermic men were obtained. The objects were divided into 3 age groups: 20-25, 30-35, and 40-45 yr. Sperm parameters and DNA fragmentation were assessed, and transcript levels of Results: The highest levels of sperm concentration, motility, and normal morphology were observed in men aged between 20 and 25 yr. Significant declines were seen in sperm total motility (p = 0.006) and normal morphology (p = 0.015) after 40 yr compared to younger men. Significantly (p Conclusion: Our findings demonstrate age-related changes in sperm
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