Evidence map›Paper›PMID 40959433›Full record

ArticleFrontiers in medicine2025

Successful treatment of pityriasis lichenoides et varioliformis acuta with stapokibart: a case report.

Rongqiao Shi, Aijuan He, Zunfeng Ma, Mengying Jiang

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rongqiao ShiGuizhou University of Traditional Chinese Medicine, Guiyang, China.
Aijuan HeDepartment of Dermatology, First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, China.
Zunfeng MaDepartment of Dermatology, First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, China.
Mengying JiangGuizhou University of Traditional Chinese Medicine, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pityriasis lichenoides et varioliformis acuta (PLEVA) is a relatively rare inflammatory skin disorder encountered in clinical practice. Stapokibart is a humanized monoclonal antibody drug targeting the interleukin receptor subunit α (IL-4Rα), and is primarily used for the treatment of atopic dermatitis. Currently, owing to the rarity of PLEVA in clinical practice, there have been no reports on the use of Stapokibart in its treatment. This article presents a case in which stapokibart was used to treat a patient with acute acneiform lichenoid pityriasis, demonstrating its clinical efficacy. Following treatment with biological agents, the patient's rash completely resolved, and their quality of life significantly improved, without any adverse reactions. This case provides a valuable reference for the clinical treatment of PLEVA.

Indexed as

case reportimmunomodulationinflammatory skin disorderpityriasis lichenoides et varioliformis acutastapokibart

Identifiers

PMID40959433
PMCPMC12434593

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.