ArticleCureus2025
Therapeutic Challenges in the Use of Chemotherapy and Cyclin-Dependent Kinase 4/6 Inhibitors in a Patient With Charcot-Marie-Tooth Disease and Breast Cancer.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a rare clinical scenario involving a 65-year-old female patient with Charcot-Marie-Tooth (CMT) disease who was diagnosed with early-stage breast carcinoma. The patient underwent neoadjuvant chemotherapy, followed by surgery and adjuvant endocrine therapy. During treatment, she developed grade 3 peripheral neuropathy, leading to the early discontinuation of paclitaxel and subsequent therapeutic adjustments. This report highlights the challenges of managing patients with neuromuscular comorbidities undergoing chemotherapy and the use of cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors as adjuvant therapy in breast cancer treatment.
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Registered trials
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