Evidence map›Paper›PMID 40959329›Full record

ArticleCureus2025

Exploring the Impact of Anxiety, Depression and Fatigue on Quality of Life Among Caregivers of Individuals With Mental Health Disorders.

Maria Monachou, Marianna Mantzorou, Georgia Fasoi, Dimos Mastrogiannis, Theodoula Adamakidou, Alexandra Koreli, Ioannis Kalemikerakis, Paraskevi Apostolara, Marianna Drakopoulou, Georgia Gerogianni

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria MonachouDepartment of Nursing, Postgraduate Program "Community and Public Health Nursing", University of West Attica, Athens, GRC.
Marianna MantzorouDepartment of Nursing, Postgraduate Program "Community and Public Health Nursing", University of West Attica, Athens, GRC.
Georgia FasoiDepartment of Nursing, Postgraduate Program "Community and Public Health Nursing", University of West Attica, Athens, GRC.
Dimos MastrogiannisDepartment of Nursing, Postgraduate Program "Community and Public Health Nursing", University of West Attica, Athens, GRC.
Theodoula AdamakidouDepartment of Nursing, Postgraduate Program "Community and Public Health Nursing", University of West Attica, Athens, GRC.
Alexandra KoreliDepartment of Nursing, Postgraduate Program "Community and Public Health Nursing", University of West Attica, Athens, GRC.
Ioannis KalemikerakisDepartment of Nursing, Postgraduate Program "Community and Public Health Nursing", University of West Attica, Athens, GRC.
Paraskevi ApostolaraDepartment of Nursing, Postgraduate Program "Community and Public Health Nursing", University of West Attica, Athens, GRC.
Marianna DrakopoulouDepartment of Nursing, Postgraduate Program "Community and Public Health Nursing", University of West Attica, Athens, GRC.
Georgia GerogianniDepartment of Nursing, Postgraduate Program "Community and Public Health Nursing", University of West Attica, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCaregivers for people diagnosed with mental health disorders can be more susceptible to experiencing increased levels of fatigue, anxiety, depression, and overall stress due to the demanding role of caregiving. This can significantly impact the physical and mental health of the care provider. The purpose of this study is to examine the impact of anxiety, depression, and fatigue on quality of life in caregivers of individuals with mental health disorders.

methodsIn this cross-sectional study, 112 caregivers of individuals with mental disorders completed the following scales: i) Hospital Anxiety and Depression Scale for the evaluation of anxiety and depression, ii) Kingston Caregiver Stress Scale for the evaluation of caregivers' stress, iii) Fatigue Severity Scale for the evaluation of fatigue, iv) SF-12 Health Survey for the evaluation of quality of life, and v) A questionnaire about demographics. Variables were tested for normality using the Kolmogorov-Smirnov criterion. Quantitative variables were expressed as mean values (standard deviation) and as median (interquartile range). Qualitative variables were expressed as absolute (N) and relative frequencies (%). Spearman correlation coefficients (rho) were used to explore the association of two continuous variables. Multiple linear regression analyses were used with the SF-12 dimensions' scores as dependent variables.

resultsIncreased fatigue, higher levels of anxiety and depression, and increased overall stress were associated with poorer physical and mental health outcomes for caregivers of people with mental health disorders (p<0.001). An increase in fatigue was also associated with higher levels of anxiety, depression, and stress (p<0.001). Caregivers with a pre-existing health problem had poorer physical health outcomes (p<0.001). An extended duration of caregiving was associated with reduced physical health (p=0.017). Parental caregivers reported low mental health (p=0.005).

conclusionsCaregiving was associated with increased fatigue, anxiety, depression and stress, leading to poorer physical and mental health outcomes for caregivers. Creating a coherent support framework that respects caregivers' needs and focuses on preventing burnout can play a key role in improving their well-being and quality of life, while strengthening the quality of care they provide.

Indexed as

anxietycaregiversdepressionfatiguepsychiatric disordersquality of life

Identifiers

PMID40959329
PMCPMC12435870

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.