SynthesisFrontiers in microbiology2025
Changes in intestinal microbiota in patients with pancreatic cancer: a systematic review and meta-analysis.
Synthesis in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Metabolic Syndrome and Pancreatic Cancer: Linking Insulin Resistance, Inflammation, and Carcinogenesis.Diagnostics (Basel, Switzerland) · 2026Review
- Tumor Location and Preoperative Biliary Stenting Shape Gut Microbiome Diversity in Pancreatic Cancer.Cancers · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pancreatic cancer (PC) is a highly aggressive malignancy with an asymptomatic early stage, often resulting in rapid invasion of adjacent tissues and organs and a high mortality rate. Recent research has increasingly examined the gut microbiome as a potential factor in PC pathogenesis. Although changes in gut microbiota composition have been reported in patients with PC, a comprehensive evaluation of the relationship between gut microbiota and PC has not been systematically conducted. Methods: A systematic search of PubMed, Web of Science, Embase, and Cochrane databases was conducted, and a meta-analysis was performed on 10 studies including a total of 324 patients with PC. Results: The meta-analysis did not identify a statistically significant difference in Conclusion: This meta-analysis demonstrates an association between PC and changes in gut microbiota composition at both the species and genus levels. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/recorddashboard, identifier CRD42023468159.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.