Evidence map›Paper›PMID 40959209›Full record

ArticleJournal of pain research2025

Acupuncture at Myofascial Trigger Points Versus Conventional Acupuncture for Knee Osteoarthritis: A Protocol for a Randomized Controlled Trial.

Chao Zhang, Hongfei Xue, Jiankang Xu, Aifeng Liu, Kuiliang Gao, Longyao Zhang

Abstract read
In one paragraph

Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chao Zhang *Orthopedics Department, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.ORCID 0000-0003-3310-3754
Hongfei Xue *Orthopedics Department, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.
Jiankang Xu *Orthopedics Department, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.
Aifeng LiuOrthopedics Department, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.ORCID 0000-0001-7318-1277
Kuiliang GaoOrthopedics Department, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.
Longyao ZhangOrthopedics Department, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.ORCID 0000-0001-5363-8575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Knee osteoarthritis (KOA) is a prevalent degenerative joint disease that significantly impacts pain and mobility. Acupuncture targeting Myofascial Trigger Points (MTrPs), guided by the "pain as acupoint" strategy, has been proposed as a more precise intervention approach. Objective: This study aims to compare the efficacy of MTrP acupuncture versus conventional acupuncture in patients with early- to mid-stage KOA. Methods: In this assessor-blinded randomized controlled trial, 106 KOA patients (Kellgren-Lawrence grade II/III) will be randomly assigned (1:1) to receive either conventional meridian-based acupuncture (Group A) or acupuncture targeting both meridian points and MTrPs (Group B). Both groups will receive treatment five times weekly for two weeks. The primary outcome is the response rate, defined as a ≥2-point reduction in VAS and ≥6-point improvement in WOMAC function score. Secondary outcomes include pressure pain threshold (PPT), three-dimensional gait analysis, and patient acceptability. Results: This study is expected to demonstrate whether MTrP acupuncture provides superior pain relief and functional improvement compared to conventional acupuncture. Conclusion: Findings will contribute novel clinical evidence for optimizing individualized acupuncture strategies in the management of KOA. Trial Registration: ChiCTR, ChiCTR2300073707, Registered on July 19, 2023.

Indexed as

acupunctureclinical trialindividualized treatmentknee osteoarthritismyofascial trigger points

Identifiers

PMID40959209
PMCPMC12435517

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.