Evidence map›Paper›PMID 40959188›Full record

ArticleHealth science reports2025

The Relationship Between Lipid Peroxidation, Serum Antioxidant Vitamin, Inflammatory Biomarker, Trace Elements, and Macro-Minerals With Bangladeshi Fibromyalgia Patients: A Case-Control Study.

Md Ashiqul Islam, Md Ashraful Alam, Shahriar Ahmed, Ahmed Rakib, Md Giash Uddin, Mohammad Nazmul Islam, Fariha Sultana Etu, Md Iftikhar Uddin Masud, S M Naim Uddin

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Md Ashiqul IslamDepartment of Pharmacy Mawlana Bhashani Science and Technology University Tangail Bangladesh.
Md Ashraful AlamDepartment of Pharmacy University of Chittagong Chittagong Bangladesh.
Shahriar AhmedDepartment of Pharmacy University of Chittagong Chittagong Bangladesh.
Ahmed RakibDepartment of Pharmacy University of Chittagong Chittagong Bangladesh.
Md Giash UddinDepartment of Pharmacy University of Chittagong Chittagong Bangladesh.ORCID https://orcid.org/0000-0003-0792-0902
Mohammad Nazmul IslamDepartment of Pharmacy International Islamic University Chittagong Chittagong Bangladesh.ORCID https://orcid.org/0000-0002-4021-106X
Fariha Sultana EtuDepartment of Pharmacy Jashore University of Science and Technology Jashore Bangladesh.
Md Iftikhar Uddin MasudNational Institute of Cardiovascular Diseases (NICVD) Dhaka Bangladesh.
S M Naim UddinDepartment of Pharmacy University of Chittagong Chittagong Bangladesh.ORCID https://orcid.org/0000-0003-4511-8697

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Fibromyalgia is an emerging health concern in Bangladesh, with symptoms that tend to worsen over time. This study sought to measure serum lipid peroxidation, nonenzymatic antioxidant, C-reactive protein (CRP), macro-minerals, and trace elements in fibromyalgia syndrome (FMS) patients to explore their association with disease progression. Methods: The investigation involved 50 fibromyalgia patients (cases) and 50 healthy individuals (controls) in Bangladesh. Serum malondialdehyde (MDA) was measured to assess lipid peroxidation utilizing spectrophotometry. UV spectrophotometric technique was employed for the determination of vitamin C, while serum levels of macro-minerals (Mg and Ca) and trace elements (Zn and Cu) were quantified using atomic absorption spectroscopy. CRP level was ascertained by using CRP-Latex agglutination assay. Results: Our study identified markedly increased levels of MDA (4.26 ± 0.04 nmol/mL, Conclusion: The findings suggest that elevated serum MDA, depleted serum concentrations of vitamin C, and altered trace elements and macro-mineral concentrations characterize the FMS patients in Bangladesh.

Indexed as

antioxidantBangladeshCRPfibromyalgiamacro‐mineralsMDAtrace elements

Identifiers

PMID40959188
PMCPMC12434171

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.