ArticleERJ open research2025
Lung involvement in rheumatoid arthritis, a prospective study.
Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Lung disease in rheumatoid arthritis.Nature reviews. Rheumatology · 2026Review
- Rheumatoid Arthritis-Associated Interstitial Lung Disease Presenting With Raynaud's Phenomenon: A Case Report.Cureus · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The prevalence of lung involvement in rheumatoid arthritis (RA) remains elusive. Therefore, we set up a multicentric prospective study to investigate the presence of interstitial lung disease (ILD), emphysema, bronchiolitis and nodules in early RA. Methods: We recruited patients with RA and a disease duration from 1 to 10 years to screening. Patients underwent comprehensive respiratory evaluation consisting of an environmental questionnaire, high-resolution computed tomography (HRCT), pulmonary function tests (PFTs) and sampling for genetic analysis of common variants associated with RA-ILD. HRCT scans were centrally reviewed. Results: We included 258 RA patients, median age 56 years old, 71% female and 49% ex- or current smokers. We detected ILD, emphysema and >20% air trapping in 38 (15%), 51 (20%) and 89 (34%) patients, respectively. Older age, male sex, disease activity and lower diffusing capacity of the lung for carbon monoxide ( Conclusions: Lung involvement affects a high proportion of early-stage RA patients, constrictive bronchiolitis being the most prevalent, followed by emphysema and ILD. Older age, uncontrolled disease, male sex and lower
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.