Evidence map›Paper›PMID 40959150›Full record

ArticleRadiology case reports2025

The role of MRI in the management of patients with a histological diagnosis of B3 breast lesion after vacuum-assisted biopsy: A case report and a brief review of the literature.

Valeria Liberto, Francesca Di Giuliano, Eleni Chatelou, Paola Elda Gigliotti, Maria Volpe, Maria Pitaro, Glenda Antonelli, Ludovica Mancini, Chiara Adriana Pistolese

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Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Valeria LibertoDepartment of Biomedicine and Prevention, University Hospital of Rome "Tor Vergata", Viale Oxford 81, Rome, Italy.
Francesca Di GiulianoDepartment of Biomedicine and Prevention, University Hospital of Rome "Tor Vergata", Viale Oxford 81, Rome, Italy.
Eleni ChatelouUniversity Hospital of Rome "Tor Vergata", Viale Oxford 81, Rome, Italy.
Paola Elda GigliottiUniversity Hospital of Rome "Tor Vergata", Viale Oxford 81, Rome, Italy.
Maria VolpeUniversity Hospital of Rome "Tor Vergata", Viale Oxford 81, Rome, Italy.
Maria PitaroUniversity Hospital of Rome "Tor Vergata", Viale Oxford 81, Rome, Italy.
Glenda AntonelliUniversity Hospital of Rome "Tor Vergata", Viale Oxford 81, Rome, Italy.
Ludovica ManciniUniversity Hospital of Rome "Tor Vergata", Viale Oxford 81, Rome, Italy.
Chiara Adriana PistoleseDepartment of Biomedicine and Prevention, University Hospital of Rome "Tor Vergata", Viale Oxford 81, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report and literature review examine the role of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in managing of breast lesions diagnosed as B3 after vacuum-assisted biopsy (VAB). A 48-year-old female patient with first-degree family history of breast cancer, whose mammography, ultrasound, and magnetic resonance imaging (MRI) showed an area of parenchymal distortion in the left upper outer quadrant (UOQ), underwent a VAB, which revealed a B3 lesion (radial scar with atypia). She subsequently underwent a vacuum-assisted excision (VAE), and a 4-month follow-up MRI showed residual enhancement in the treated area; after a multidisciplinary discussion, she underwent surgery, which confirmed the complex sclerosing lesion (CLS) with atypia. The authors highlight the importance of MRI's high negative predictive value in excluding malignancy, especially in conjunction with VAE, which allows for more comprehensive tissue sampling and reduces the need for surgical excision in B3 cases. The multidisciplinary approach and correlation of radiological and pathological findings are emphasized as crucial for optimal patient management.

Indexed as

AtypiaDynamic contrast-enhanced magnetic resonance imagingRadial scarVacuum-assisted biopsy

Identifiers

PMID40959150
PMCPMC12435004

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