Evidence map›Paper›PMID 40959129›Full record

ArticleInternational journal of reproductive biomedicine2025

Carob extract restores testicular function and sperm quality in cadmium-exposed mice: An experimental study.

Mojtaba Moradi, Elham Ghanbari, Zahra Rashidi, Saman Moradi, Ali Shakeri, Azita Faramarzi

Abstract read
In one paragraph

Article in International journal of reproductive biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mojtaba MoradiFertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Elham GhanbariDepartment of Tissue Engineering, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Zahra RashidiDepartment of Anatomical Sciences, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Saman MoradiTissue Engineering and Applied Cell Sciences Division, Department of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Ali ShakeriStudent Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Azita FaramarziDepartment of Anatomical Sciences, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cadmium (Cd) is a hazardous heavy metal, and its exposure can lead to a range of health issues, including significant adverse effects on reproductive health in animals and humans. Recently, there has been increasing recognition of the antioxidant benefits of Objective: To evaluate the therapeutic potential of CSE in mitigating testicular injury and spermatogenesis impairment induced by Cd. Materials and Methods: In this experimental study, 40 adult male BALB/c mice (8-12 wk, 30 Results: CSE restored spermatogenesis by improving sperm count, motility, viability, morphology, and chromatin integrity (p Conclusion: Administering CSE could potentially enhance testis function and sperm parameters against chronic Cd exposure-induced reproductive toxicity, likely due to improving testosterone secretion and its antioxidant properties.

Indexed as

CadmiumCeratonia siliquaMiceOxidative stressSpermatozoa.

Identifiers

PMID40959129
PMCPMC12435346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.