Evidence map›Paper›PMID 40959032›Full record

ArticleJSES international2025

Initiation and progression of rotator cuff tears due to fatigue loading: a cadaveric study.

Mason J Garcia, Daniela Caro, Alberto Lalli, Giovanni Intermesoli, Arun J Ramappa, Joseph P DeAngelis, Umile Giuseppe Longo, Ara Nazarian

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Article in JSES international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mason J GarciaMusculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Daniela CaroMusculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Alberto LalliFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Giovanni IntermesoliFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Arun J RamappaMusculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Joseph P DeAngelisMusculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Umile Giuseppe LongoFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Ara NazarianMusculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Rotator cuff (RC) tears are one of the most common tendinous injuries in the adult population, resulting in pain and loss of function. While many tears are often asymptomatic, many patients will experience tears progression and the development of symptoms. The objective of this study is to determine the location of RC tear initiation and the subsequent biomechanical changes as a function of tear size. Methods: 8 fresh-frozen (n = 8) human cadaveric supraspinatus tendons (mean age: 68.6 ± 14.2) were subjected to fatigue loading. Images were taken to capture the location of tear initiation and subsequent progression. Tendon stiffness and nominal strain were measured throughout the tendon's lifecycle to determine changes to the biomechanical properties as a function of tear size. Results: The location of tear initiation was 15.89 Conclusion: In a biomechanical model of RC tears induced by fatigue loading, tear initiation was observed approximately 16 mm posterior to the biceps tendon, positioning it further posterior than previously believed. Alterations to the biomechanical properties occur due to tear progression. However, these changes are most severe and significant when tears progress to >100 mm

Indexed as

Cadaveric studyFatigue loadingFinite element modelingRotator cuff tearsSupraspinatus tendonTear progressionTendon biomechanicsTendon stiffness and strai

Identifiers

PMID40959032
PMCPMC12435029

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.