Evidence map›Paper›PMID 40959002›Full record

ArticleJSES international2025

Accuracy of clinical symptoms and nuclear imaging in the diagnosis of infection in revision shoulder arthroplasty.

Cristina Bassi, Diane Nam, Elham Sabri, Darren Drosdowech, J W Pollock, Dominique Rouleau, Taryn Hodgdon, Katie McIlquham, Jonathan Doyon, Peter Lapner

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Article in JSES international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Cristina BassiDivision of Orthopaedic Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Diane NamDivision of Orthopaedic Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Elham SabriThe Ottawa Methods Centre, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Darren DrosdowechRoth McFarlane Hand and Upper Limb Centre, St. Joseph's Health Care, Western University, London, ON, Canada.
J W PollockDivision of Orthopaedic Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Dominique RouleauDivision of Orthopaedic Surgery, Hôpital du Sacré-Cœur-de-Montréal, Université de Montréal, Montréal, QC, Canada.
Taryn HodgdonDepartment of Medical Imaging, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Katie McIlquhamDivision of Orthopaedic Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Jonathan DoyonDivision of Orthopaedic Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Peter LapnerDivision of Orthopaedic Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prosthetic shoulder infection is the most common reason for revision arthroplasty within 2 years of the index procedure. Due to the preponderance of indolent and slow-growing infection in shoulder arthroplasty, establishing a diagnosis of infection prior to revision shoulder arthroplasty can be extremely difficult. The aim of this study was to determine the association between specific clinical symptoms and signs as well as nuclear imaging results with culture positive status in revision shoulder arthroplasty. Methods: This study is a secondary analysis of a multicenter prospective cohort study involving 4 sites and 69 patients who underwent revision shoulder arthroplasty. The cohort was 60% female with a mean age of 64 years (range 36-83 years). Outcomes of interest included preoperative specific clinical symptoms (pain at rest, fevers, chills, and sweats); and white blood cell (WBC) nuclear scan results. At least 5 synovial tissue biopsies from separate regions in the shoulder were obtained intra-operatively during revision surgery. Results: Twenty-three percent of patients (n = 16) had confirmed culture positive infections based on the open biopsies. Sixty-four percent of patients presented with pain at rest. Pain at rest ( Conclusion: This study suggests that specific clinical symptoms including pain at rest, systemic symptoms including fevers, chills, or sweats, and WBC bone scan are poorly associated with the presence of infection in revision shoulder arthroplasty. These findings point to the need for novel testing methods to establish the presence of infection in this patient population.

Indexed as

C. acnesOpen cultureProsthetic joint infectionRevisionShoulder arthroplastyShoulder infection

Identifiers

PMID40959002
PMCPMC12434946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.