Evidence map›Paper›PMID 40958824›Full record

ArticleJAAD international2025

Expert consensus-based recommendations on the use of photodynamic therapy in actinic keratosis patients.

Vishal A Patel, Sarah T Arron, Brian Berman, M Shane Chapman, Anokhi Jambusaria-Pahlajani, George Martin, Anthony M Rossi, Todd Schlesinger, Nathalie C Zeitouni, Neal Bhatia

Abstract read
In one paragraph

Article in JAAD international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Photodynamic Therapy in Dermatology.International journal of molecular sciences · 2026
    Review
  5. Article
  6. Skin Cancer in Solid Organ Transplant Recipients: A Review.American journal of clinical dermatology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vishal A PatelDepartment of Dermatology, George Washington University School of Medicine & Health Sciences, Washington, District of Columbia.
Sarah T ArronPeninsula Dermatology, Burlingame, California.
Brian BermanUniversity of Miami Miller School of Medicine, Miami, Florida.
M Shane ChapmanDepartment of Dermatology, Dartmouth Hitchcock Medical Center, Nashua, New Hampshire.
Anokhi Jambusaria-PahlajaniDivision of Dermatology, Department of Internal Medicine, The University of Texas at Austin Dell Medical School, Austin, Texas.
George MartinDr. George Martin Dermatology Associates, Kihei, Hawaii.
Anthony M RossiMemorial Sloan Kettering Cancer Center, New York, New York.
Todd SchlesingerClinical Research Center of the Carolinas, Charleston, South Carolina.
Nathalie C ZeitouniMedical Dermatology Specialists, Phoenix, Arizona.
Neal BhatiaTherapeutics Clinical Research, San Diego, California.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Background: Current actinic keratosis (AK) treatment guidelines are controversial and incomplete, leaving an unmet need for clearer and more in-depth guidance on the usage of photodynamic therapy (PDT) in AKs. Objective: To gain consensus on the use of PDT for AKs using a modified Delphi method. Methods: Consensus statements were developed after a literature review of topics surrounding PDT and AKs. Ten panelists voted through electronic questionnaires rating each statement on a three-point Likert-type scale: strongly agree, agree, and disagree. Consensus was established when ≥70% of panelists strongly agreed on the statement. Statements that did not meet the threshold were revised after each round of voting and sent out for the next round of voting. A virtual meeting was held after 2 rounds of voting to discuss outstanding statements. Results: Three modified Delphi rounds were completed in total and 1 virtual meeting was held. All 10 experts responded to all rounds of voting. A total of 55 statements established consensus with the ≥70% majority requirement necessary. Limitations: Recommendations are based on expert opinions. Conclusion: The results from this consensus panel are intended to bridge gaps in the existing guidelines and will continue to evolve.

Indexed as

actinic keratosisaminolevulinic acid (ALA)basal cell carcinoma (BCC)cutaneous squamous cell carcinoma (cSCC)field therapyorgan transplant recipientsphotodynamic therapyred light

Identifiers

PMID40958824
PMCPMC12433913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.