Evidence map›Paper›PMID 40958762›Full record

ArticlePlant biotechnology journal2026

Glucuronoyl Esterase of Pathogenic Phanerochaete carnosa Induces Immune Responses in Aspen Independently of Its Enzymatic Activity.

Evgeniy N Donev, Marta Derba-Maceluch, Xiao-Kun Liu, Henri Colyn Bwanika, Izabela Dobrowolska, Mohit Thapa, Joanna Leśniewska, Jan Šimura, Alex Yi-Lin Tsai, Konrad S Krajewski and 6 more

Abstract read
In one paragraph

Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Evgeniy N DonevUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.ORCID https://orcid.org/0000-0002-7279-0481
Marta Derba-MaceluchUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.ORCID https://orcid.org/0000-0002-8034-3630
Xiao-Kun LiuUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.ORCID https://orcid.org/0000-0002-4889-8361
Henri Colyn BwanikaUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.ORCID https://orcid.org/0000-0002-0834-4153
Izabela DobrowolskaUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.
Mohit ThapaUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.
Joanna LeśniewskaUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.ORCID https://orcid.org/0000-0002-2810-4165
Jan ŠimuraUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.ORCID https://orcid.org/0000-0002-1567-2278
Alex Yi-Lin TsaiDepartment of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.
Konrad S KrajewskiUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.ORCID https://orcid.org/0000-0002-1534-4311
Dan BoströmDepartment of Applied Physics and Electronics, Umeå University, Umeå, Sweden.
Leszek A KleczkowskiUmeå Plant Science Centre (UPSC), Department of Plant Physiology, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0001-8685-9665
Maria E ErikssonUmeå Plant Science Centre (UPSC), Department of Plant Physiology, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0003-2038-4892
Karin LjungUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.ORCID https://orcid.org/0000-0003-2901-189X
Emma R MasterDepartment of Chemical Engineering & Applied Chemistry, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-6837-9817
Ewa J MellerowiczUmeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.ORCID https://orcid.org/0000-0001-6817-1031

Funding

Knut och Alice Wallenbergs StiftelseNils and Dorthi TroëdssonsStiftelsen för Strategisk Forskning project ValueTree RBP14-0011Svenska Forskningsrådet FormasVetenskapsrådetVINNOVA
6 · The paper itself

Abstract

Microbial enzymes expressed in plants add new functionalities but occasionally trigger undesirable immune responses. Phanerochaete carnosa glucuronoyl esterase (PcGCE) hydrolyses the bond between lignin and 4-O-methyl-α-D-glucuronic acid substituent of glucuronoxylan. PcGCE constitutively expressed in Arabidopsis or hybrid aspen (Populus tremula × tremuloides) improved saccharification but also induced premature leaf senescence. To understand what triggered this senescence, we characterised PcGCE-expressing hybrid aspen by microscopy and omics approaches, supplemented by grafting and recombinant protein application experiments. PcGCE induced massive immune responses followed by senescence in the leaves. Expressing an inactive (PcGCE

Indexed as

EsterasesFungal ProteinsPhanerochaetePlant ImmunityPopulusArabidopsisPlant DiseasesPlant LeavesPlants, Genetically ModifiedEsterasesFungal Proteinsbiotic stressglucuronoyl esteraselignocellulose improvementPopulusPTItransgenic cropsunfolded protein response

Identifiers

PMID40958762
PMCPMC12906814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.