Evidence map›Paper›PMID 40958620›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2025

DurAVR - a novel biomimetic balloon-expandable transcatheter valve for TAVI, valve-in-valve TAVI and redo-TAVI.

David Meier, Julien Delarive, Althea Lai, Rebecca T Hahn, João L Cavalcante, Anita W Asgar, Azeem Latib, Pankaj Garg, Susheel Kodali, Vinayak N Bapat and 4 more

Abstract read
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Innovation and Challenges in Materials for Transcatheter Aortic Valves.Journal of cardiovascular translational research · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

David MeierDepartment of Cardiology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Julien DelariveDepartment of Cardiology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Althea LaiCardiovascular Translational Laboratory, Providence Research & Centre for Heart Lung Innovation, Vancouver, BC, Canada.
Rebecca T HahnCardiology Department, NewYork-Presbyterian/Columbia University Medical Center, New York, NY, USA.
João L CavalcanteMinneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.
Anita W AsgarStructural Heart Program, Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, IL, USA.
Azeem LatibMontefiore Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Pankaj GargNorwich Medical School, University of East Anglia, Norwich, United Kingdom.
Susheel KodaliColumbia University Irving Medical Center and NewYork-Presbyterian Hospital, New York, NY, USA.
Vinayak N BapatMinneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.
Magnus SettergrenDepartment of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Janarthanan SathananthanCentre for Cardiovascular Innovation, St Paul's Hospital, Vancouver, BC, Canada.
Christopher U MeduriDepartment of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Stephanie L SellersCardiovascular Translational Laboratory, Providence Research & Centre for Heart Lung Innovation, Vancouver, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe DurAVR transcatheter heart valve (THV) is a novel biomimetic balloon-expandable valve with promising early clinical results.

aimsWe aimed to assess the hydrodynamic performance of the DurAVR THV in native, valve-in-valve (ViV), and redo-transcatheter aortic valve implantation (TAVI) procedures against commercially available THVs on the bench.

methodsThe hydrodynamic function of the DurAVR THV was assessed by simulating native valve deployments at 0 mm, 3 mm, and 6 mm depths, compared to SAPIEN 3 (S3), Evolut PRO, Navitor, and ACURATE neo2 (ACn2) valves. For ViV simulations, THVs were implanted in 21 mm and 23 mm Magna Ease, Mosaic, and Hancock bioprostheses. For redo-TAVI simulations, the DurAVR THV was assessed within S3, Evolut PRO, Navitor, and ACn2 valves.

resultsFor native TAVI simulations, the DurAVR THV demonstrated superior or comparable hydrodynamic performance, independent of implant depth, with an effective orifice area (EOA) ≥3 cm

conclusionsIn this bench study, the DurAVR THV demonstrated excellent hydrodynamic performance in native, ViV, and redo-TAVI simulations. Future large-scale studies are needed to confirm these findings in clinical application and further characterise the valve's short- and long-term performance.

Indexed as

Aortic ValveAortic Valve StenosisBioprosthesisHeart Valve ProsthesisTranscatheter Aortic Valve ReplacementHeart Valve Prosthesis ImplantationHemodynamicsHumansHydrodynamicsProsthesis DesignReoperation

Identifiers

PMID40958620
PMCPMC12438964

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.