Evidence map›Paper›PMID 40958586›Full record

ArticleCancer2025

Sexual health among Danish cancer survivors and individuals with no history of cancer: Baseline findings from the nationwide Project SEXUS cohort study.

Cecilie H Madsen, Christian Graugaard, Susanne O Dalton, Mikael Andersson, Pernille E Bidstrup, Morten Frisch

Abstract read
In one paragraph

Article in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cecilie H MadsenPsychological Aspects of Cancer, Cancer Survivorship, Danish Cancer Institute, Copenhagen, Denmark.ORCID https://orcid.org/0009-0009-9540-7527
Christian GraugaardDepartment of Clinical Medicine, The Faculty of Medicine, Center for Sexology Research, Aalborg University, Aalborg, Denmark.ORCID https://orcid.org/0000-0003-0217-3637
Susanne O DaltonCancer Survivorship, Danish Cancer Institute, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-5485-2730
Mikael AnderssonDepartment of Epidemiology Research, Project SEXUS Group, Statens Serum Institut, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-0114-2057
Pernille E BidstrupPsychological Aspects of Cancer, Cancer Survivorship, Danish Cancer Institute, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-9704-6800
Morten FrischDepartment of Clinical Medicine, The Faculty of Medicine, Center for Sexology Research, Aalborg University, Aalborg, Denmark.ORCID https://orcid.org/0000-0002-3864-8860

Funding

Fabrikant Einar Willumsens MindelegatThe Danish Cancer Society R303-A17458-21-S3The Danish Health Insurance Foundation 22-B-0218
6 · The paper itself

Abstract

introductionBeing diagnosed with and treated for cancer often results in physical symptoms and psychosocial distress that may affect sexual health. This population-based study in Denmark aimed to compare the sexual health of cancer survivors across multiple cancer sites with that of individuals with no history of cancer.

methodsData were used from 4085 cancer survivors and 58,590 individuals without cancer aged 15 to 89 years, who participated in the nationally representative Project SEXUS cohort study. Prevalence estimates for sexual outcomes were calculated, and logistic regression analyses yielded confounder-adjusted odds ratios (aORs) with 95% confidence intervals (CIs) for associations of cancer survivorship with sexual outcomes, both overall and across cancer sites.

resultsCancer survivors experienced significantly more sexual challenges than individuals without cancer, both overall and in the first 5 years after their most recent cancer diagnosis. This difference was seen across multiple cancer sites and regardless of age at diagnosis (<60 vs. ≥60 years). Among several statistically significant findings, particularly high aORs were noted for dissatisfaction with breast appearance (aOR: 1.89; CI, 1.49-2.41) and genital pain dysfunction (aOR: 1.74; CI, 1.32-2.28) among women and lack of sexual needs (aOR: 1.93; CI, 1.61-2.30) and erectile dysfunction (aOR: 2.79; CI, 2.30-3.38) among men.

conclusionCompared to individuals with no history of cancer, sexual health was significantly affected among cancer survivors of both sexes and across cancer sites, time since diagnosis, and age at diagnosis. Health care professionals should recognize and routinely address the sexual challenges experienced by cancer survivors to enhance their biopsychosocial recovery.

Indexed as

Cancer SurvivorsNeoplasmsSexual BehaviorSexual HealthAdolescentAdultAgedAged, 80 and overCohort StudiesDenmarkFemaleHumansMaleMiddle AgedSexual Dysfunction, PhysiologicalYoung Adultcancer rehabilitationcancer survivorsneoplasmonco‐sexologypopulation studysexual dysfunctionsexual health

Identifiers

PMID40958586
PMCPMC12441660

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.