Evidence map›Paper›PMID 40958562›Full record

ArticleThe Journal of veterinary medical science2025

Prevalence, antimicrobial susceptibility, and virulence profiles of fluoroquinolone-resistant Escherichia coli isolated from companion animals in Sapporo, Japan.

Aiko Maeda, Toyotaka Sato, Jirachaya Toyting-Hiraishi, Akio Suzuki, Yuuji Hoshino, Shingo Torigoe, Keiichiro Sakakibara, Satoshi Tamai, Tooru Tachibana, Motohiro Horiuchi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A community-based One Health approach to the pandemic dynamics ofAntimicrobial agents and chemotherapy · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aiko MaedaLaboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.
Toyotaka SatoLaboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.
Jirachaya Toyting-HiraishiLaboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.
Akio SuzukiLaboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.
Yuuji HoshinoKikusui Small Animal Hospital, Hokkaido, Japan.
Shingo TorigoeAinosato Animal Hospital, Hokkaido, Japan.
Keiichiro SakakibaraNorth Animal Clinic, Hokkaido, Japan.
Satoshi TamaiTamai Animal Hospital, Hokkaido, Japan.
Tooru TachibanaHokko Animal Hospital, Hokkaido, Japan.
Motohiro HoriuchiLaboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance in Escherichia coli is a growing concern in both human and veterinary medicine. Although fluoroquinolone-resistant (FQ-R) E. coli has been reported in companion animals, no integrated analysis incorporating antimicrobial susceptibility, clonality, resistance genes, and virulence factors (VFs) to assess human health risks has been conducted in Japan. This study aimed to characterize FQ-R E. coli isolates from companion animals in Sapporo, Japan by identifying antimicrobial susceptibility, clonality, resistance genes, and VFs. Among 106 animals sampled, 33.0% carried FQ-R E. coli. Among 104 FQ-R E. coli isolates, 58 isolates (55.8%) were identified as ST131. Whole-genome sequencing of 35 representative FQ-R E. coli isolates, including 20 ST131 isolates, showed that the ST131 isolates were distributed among five clades/sub-clades (C1-nM27, C1-M27, A, C2 and Unclassified), indicating increased clade diversity compared to previous years. ST1193, another international high-risk clone, was also detected. All isolates harbored mutations of quinolone resistance-determining regions in gyrA and parC, and 51.4% carried bla

Indexed as

Anti-Bacterial AgentsCat DiseasesDog DiseasesDrug Resistance, BacterialEscherichia coliEscherichia coli InfectionsFluoroquinolonesPetsAnimalsCatsDogsJapanMicrobial Sensitivity TestsPrevalenceVirulenceVirulence FactorsAnti-Bacterial AgentsFluoroquinolonesVirulence Factorsantimicrobial resistancecompanion animalEscherichia colifluoroquinolone resistance

Identifiers

PMID40958562
PMCPMC12604948

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.