Evidence map›Paper›PMID 40958544›Full record

ArticleJournal of bone metabolism2025

Association of Low Muscle Mass, Weak Grip Strength, and Neutrophil-to-Lymphocyte Ratio in Old Ages.

Jungha Park, Hyeon Ju Kim, Mi Hee Kong, Ji Hyun Moon

Abstract read
In one paragraph

Article in Journal of bone metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jungha ParkDepartment of Family Medicine, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.
Hyeon Ju KimDepartment of Family Medicine, Jeju National University Hospital, Jeju, Korea.
Mi Hee KongDepartment of Family Medicine, Jeju National University Hospital, Jeju, Korea.
Ji Hyun MoonDepartment of Family Medicine, Jeju National University Hospital, Jeju, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia is an age-related disease, and is assumed to be associated with systemic inflammation. We examined the relationship between the neutrophil-to-lymphocyte ratio (NLR), an easily accessible inflammatory marker, and sarcopenia in older adults.

methodsThis retrospective cross-sectional study, medical records of patients visiting a tertiary hospital's health check-up center were analyzed. The study included older adults aged 60 and over, and who had their grip strength, skeletal muscle mass, and complete blood count with differential tests measured. In this study, sarcopenia was defined as the presence of both low muscle mass and weak grip strength according to the Asian Working Group for Sarcopenia 2019 criteria.

resultsOf the 2,385 participants, 74 participants (3.10%) had sarcopenia. The non-sarcopenia group was younger than the sarcopenia group (mean age, 65.8±5.4 vs. 73.2±7.5). The average NLR of participants without sarcopenia was 1.75±0.97 and the average NLR of participants with sarcopenia was 2.08±1.11 (P=0.004). The number of participants with sarcopenia increased across higher NLR quintile (P for trend=0.016), as well as those with low skeletal muscle mass (P for trend<0.001) and weak grip strength (P for trend=0.009).

conclusionsOlder adults with a high NLR may be considered for sarcopenia screening.

Indexed as

AgedHand strengthLymphocytesNeutrophilsPrimary health careSarcopenia

Identifiers

PMID40958544
PMCPMC12444080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.