Evidence map›Paper›PMID 40958484›Full record

ArticleInfection & chemotherapy2025

Clinical Burden of Pediatric Influenza A and B in Malaysia: Outcomes and Resource Utilization in A Tropical Setting.

Vishnu Arvindran Chandra Mohan, Chuin-Hen Liew, Kah Kee Tan, Naveen Nair Gangadaran, Pon Ling Lau, Syaniza Shaharudin, Yasothai Chandran, Asuwani Maran, Farah Nuruliayana A Nazri, Hui Yi Lim and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection & chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Vishnu Arvindran Chandra MohanHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0009-0002-0153-4576
Chuin-Hen LiewHospital Tuanku Ampuan Najihah, Jalan Melang, Kuala Pilah, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0000-0001-8775-0303
Kah Kee TanFaculty of Medicine & Health Sciences, UCSI University Springhill (Seremban/PD) Campus, Persiaran Springhill, Port Dickson, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0000-0002-8445-5816
Naveen Nair GangadaranHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0000-0003-3359-8646
Pon Ling LauHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0009-0008-6740-513X
Syaniza ShaharudinHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0000-0002-2757-4894
Yasothai ChandranHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0009-0002-2965-7375
Asuwani MaranHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0009-0007-3920-6881
Farah Nuruliayana A NazriHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0009-0002-4156-7380
Hui Yi LimHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0009-0005-7467-1864
Xiang Lin ChengHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0009-0000-5789-5499
Muhammad Ihsan RoslanHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0009-0002-1958-3755
Joanne PereiraHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0009-0005-9901-6444
Nur Ainaa Najwa RazaliHospital Tuanku Ampuan Najihah, Jalan Melang, Kuala Pilah, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0009-0003-6654-238X
Marlindawati Mohd AliHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia.ORCID https://orcid.org/0000-0002-7367-4466
David Chun-Ern NgHospital Tuanku Ja'afar, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia. davidngce@gmail.com.ORCID https://orcid.org/0000-0001-9665-3054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfluenza is a leading cause of pediatric respiratory illness globally, yet comparative data on influenza A and B in tropical regions remain scarce. This study aimed to compare clinical features, healthcare utilization, and outcomes in children hospitalized with laboratory-confirmed influenza A and B. MATERIALS AND

methodsWe conducted a retrospective cross-sectional study of children aged ≤12 years hospitalized with laboratory-confirmed influenza at a tertiary referral centre from May 2022 to December 2023. Influenza diagnosis was established using antigen-based detection via direct fluorescent antibody testing. Demographics, clinical features, laboratory results, interventions received, and patient outcomes were analyzed.

resultsAmong 177 hospitalized children, 116 (65.5%) had influenza A and 61 (34.5%) had influenza B. Seizures were significantly more common in influenza A (27.6%

conclusionInfluenza A was more frequently associated with neurologic manifestations, whereas influenza B showed a higher prevalence of lower respiratory and gastrointestinal symptoms and required greater supportive care. These findings highlight the distinct clinical profiles of influenza A and B and their implications for healthcare resource utilization.

Indexed as

Clinical manifestationsInfluenza burdenInfluenza vaccinationPediatric influenzaVictoria lineage

Identifiers

PMID40958484
PMCPMC12511758

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.