ArticleJournal of sleep research2026
Sleep and Trajectories of Respiratory and Allergic Symptoms Between 1 and 5.5 Years of Age in the Elfe Birth Cohort.
Article in Journal of sleep research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Sleep and Trajectories of Respiratory and Allergic Symptoms Between 1 and 5.5 Years of Age in the Elfe Birth Cohort.Journal of sleep research · 2026Article
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11 authors.
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Abstract
Sleep troubles and respiratory and allergic health issues are associated in children, but the timeline of their association is overlooked. This study investigates the associations between sleep patterns at age 1 and respiratory and allergic multi-trajectories (RespA-MTG) between ages 1 and 5.5, and the associations between these multi-trajectories and sleep at age 5.5 in the ELFE birth cohort. Sleep clusters at ages 1 and 5.5 (based on nocturnal and diurnal sleep duration, sleep onset difficulties, and night awakenings) and RespA-MTG between ages 1 and 5.5 (based on wheezing, asthma medication, eczema, allergic conjunctivitis) were identified using data-driven methods. Associations between sleep clusters and RespA-MTG were assessed using multinomial regressions adjusted for confounders in 9577 children. Two sleep clusters were identified at ages 1 and 5.5: good sleepers (79.9% at age 1, 83.1% at 5.5) and poor sleepers (20.1% and 16.9%, respectively). Four RespA-MTG were identified: pauci-symptomatic (44.4%), persistent non-respiratory allergic symptoms (23.1%), transient early respiratory symptoms (25.2%), and persistent respiratory and allergic symptoms (7.3%). Poor sleep at age 1 was associated with higher odds of transient early respiratory symptoms (Odds Ratio [95% Confidence Interval], 1.14 [0.99-1.31]) and persistent respiratory and allergic symptoms (1.29 [1.05-1.59]). Results were reinforced in children without wheezing at 2 months. A borderline association was observed between persistent respiratory and allergic symptoms and sleep at 5.5 in good sleepers at 1 year (1.22 [0.98-1.50]). In conclusion, sleep disturbances at age 1 are associated with later poorer respiratory and allergic health, suggesting early sleep troubles may predict these health concerns.
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