ReviewCardiovascular and interventional radiology2025
Genicular Artery Embolization for Symptomatic Knee Osteoarthritis: A Comprehensive Review of Techniques and Clinical Outcomes.
Review in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Genicular Artery Embolization Using Imipenem/Cilastatin vs. Microsphere for Knee Osteoarthritis (GAUCHO). 12-Month Clinical Results of a Single-blind Randomized Controlled Trial.Cardiovascular and interventional radiology · 2026Trial
- Multi-site efficacy and safety of transarterial microembolization with imipenem/cilastatin for refractory musculoskeletal pain: a single-centre analysis of hip, knee and shoulder (FIRE-NEM study).La Radiologia medica · 2026Article
- Acupuncture suppresses the endoplasmic reticulum stress-c-Jun N-terminal kinase pathway to inhibit chondrocyte apoptosis and attenuate knee osteoarthritis.Cell stress & chaperones · 2026Article
- Genicular Artery Embolization (GAE) for the Treatment of Advanced Knee Osteoarthritis in Selected Nonoperative Patients: A Pilot Study at 6 Months Follow-Up.Journal of clinical medicine · 2026Article
- Genicular Artery Embolization for Chronic Exudative Knee Synovitis: Prospective 6-Month Clinical and Functional Outcomes.Journal of clinical medicine · 2026Article
- Temporary Versus Permanent Embolization in Genicular Artery Embolization: Does Embolic Choice Matter?Cardiovascular and interventional radiology · 2026Article
- Repeated Genicular Artery Embolization Using Permanent Microspheres for Severe Osteoarthritis and Postsurgical Pain.Cardiovascular and interventional radiology · 2026Observational
- Segmentation of blush size guides embolic endpoints in genicular artery embolization.European radiology · 2026Article
- Repeated Genicular Artery Embolization Using Permanent Microspheres for Severe Osteoarthritis and Postsurgical Pain.Cardiovascular and interventional radiology · 2026Article
- Genicular Artery Embolization for Knee Osteoarthritis: Do Degradable Starch Microspheres Offer a New Therapeutic Option?Cardiovascular and interventional radiology · 2026Article
- Genicular Artery Embolization for Knee Osteoarthritis: An Interventional Radiology Perspective on Pathophysiology, Imaging Biomarkers and Procedural Strategy.Diagnostics (Basel, Switzerland) · 2026Review
- Genicular Artery Embolization Using Resorbable Gelatin Microspheres for Refractory Knee Pain: Technique, Safety and Clinical Outcome.Cardiovascular and interventional radiology · 2026Observational
- We Saved the Best for Last….Cardiovascular and interventional radiology · 2025Article
- We Saved the Best for Last….Cardiovascular and interventional radiology · 2025Article
- We Saved the Best for Last….Cardiovascular and interventional radiology · 2025Article
- We Saved the Best for Last….Cardiovascular and interventional radiology · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSymptomatic knee osteoarthritis is the most common joint disorder worldwide. Genicular artery embolization (GAE) is a minimally invasive therapy targeting abnormal knee neovascularity and inflammation, with potential to alter management paradigms. This review summarizes key evidence on its rationale, techniques, outcomes, and the need for standardization. MATERIALS AND
methodsPeer-reviewed studies on GAE for knee osteoarthritis were assessed for patient selection, procedural technique, embolic agents, and reported outcomes.
resultsGAE consistently achieved high technical success and short- to mid-term pain reduction, with improved VAS, WOMAC, and KOOS scores. Temporary and permanent embolic agents provide comparable results. Variability in vessel targets, embolic size, and periprocedural protocols limits direct comparisons and pooled analysis. Reported adverse events are uncommon, generally mild, and self-limited.
conclusionsGAE offers a promising, image-guided option for symptomatic knee osteoarthritis. Standardized procedural methods, uniform outcome reporting, and robust multicenter trials are needed to confirm long-term safety and efficacy, optimize patient selection, and define GAE's role in osteoarthritis management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.