Evidence map›Paper›PMID 40958039›Full record

SynthesisEuropean geriatric medicine2025

Physical activity interventions for hospitalised people living with dementia: systematic review and meta-analysis.

Emma Elliott, Jodi Ventre, Sarah Kate Smith, William Carey, Charlotte Eost-Telling, Annemarie Money, Toby Bryce-Jones, Victoria Dickens, Chris J Todd, Emma R L C Vardy

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European geriatric medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emma ElliottNIHR-ARC Greater Manchester, School of Health Sciences, The University of Manchester, The University of Manchester, Jean McFarlane Building, Oxford Road, Manchester, M13 9PL, UK. emma.elliott@manchester.ac.uk.ORCID http://orcid.org/0000-0002-4323-9308
Jodi VentreNIHR-ARC Greater Manchester, School of Health Sciences, The University of Manchester, The University of Manchester, Jean McFarlane Building, Oxford Road, Manchester, M13 9PL, UK.
Sarah Kate SmithNIHR-ARC Greater Manchester, School of Health Sciences, The University of Manchester, The University of Manchester, Jean McFarlane Building, Oxford Road, Manchester, M13 9PL, UK.
William CareyNorthern Care Alliance NHS Foundation Trust, Salford, UK.
Charlotte Eost-TellingNIHR-ARC Greater Manchester, School of Health Sciences, The University of Manchester, The University of Manchester, Jean McFarlane Building, Oxford Road, Manchester, M13 9PL, UK.
Annemarie MoneyNIHR-ARC Greater Manchester, School of Health Sciences, The University of Manchester, The University of Manchester, Jean McFarlane Building, Oxford Road, Manchester, M13 9PL, UK.
Toby Bryce-JonesUniversity Hospitals of Leicester NHS Trust, Leicester, UK.
Victoria DickensNorthern Care Alliance NHS Foundation Trust, Salford, UK.
Chris J ToddNIHR-ARC Greater Manchester, School of Health Sciences, The University of Manchester, The University of Manchester, Jean McFarlane Building, Oxford Road, Manchester, M13 9PL, UK.
Emma R L C VardyNIHR-ARC Greater Manchester, School of Health Sciences, The University of Manchester, The University of Manchester, Jean McFarlane Building, Oxford Road, Manchester, M13 9PL, UK.

Funding

National Institute for Health and Care Research NIHR200174
6 · The paper itself

Abstract

purposePeople living with dementia are vulnerable to adverse outcomes of hospitalisation, such as functional decline and deconditioning. The aim of this review was to examine the effectiveness of hospital-based interventions involving physical activity on deconditioning outcomes in people living with dementia.

methodsFive databases (MEDLINE, CENTRAL, Embase, PsycINFO, and CINAHL) were searched to January 2025 to identify eligible studies. Two researchers independently carried out screening, data extraction and quality assessment. INCLUSION CRITERIA: adults with a diagnosis of dementia, acute hospital admission, and interventions involving physical activity during hospitalisation. Data were pooled for strength, balance, functional outcomes, readmission, falls, length of stay, and delirium. We used GRADE to assess the certainty of evidence.

results2179 records were identified and six studies (n = 576 with dementia) included: one randomised-controlled trial, five non-randomised or quasi-randomised. Studies were conducted in an "acute care for elders unit" (n = 2), acute psychogeriatric ward (n = 2), general medical unit (n = 1), and geriatric rehabilitation ward (n = 1) across six countries. In meta-analyses, there was less decline in basic activities of daily living at 3 months in the physical activity group (change from pre-admission status); two studies, mean difference 1.27 (95% CI 0.36-2.18) but there were no differences found in all other outcomes at discharge or 3 months, compared to usual care. Certainty of the evidence is low/very low.

conclusionDue to the limited available evidence, there is uncertainty about the effect of physical activity interventions above usual care. More high-quality research is needed to improve outcomes for people living with dementia in hospital.

Indexed as

DementiaExerciseHospitalizationAccidental FallsActivities of Daily LivingAgedHumansDeconditioningDementiaExerciseFunctional declineHospitalisationPhysical activity

Identifiers

PMID40958039
PMCPMC12743704

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.