Evidence map›Paper›PMID 40957971›Full record

ArticleSurgical endoscopy2025

Efficacy and safety of endoscopic submucosal dissection for pyloric neoplasms.

Shao-Bin Luo, Zu-Qiang Liu, Li Wang, Yi-Qun Zhang, Ming-Yan Cai, Quan-Lin Li, Ping-Hong Zhou

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shao-Bin LuoEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Zu-Qiang LiuEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Li WangEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yi-Qun ZhangEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Ming-Yan CaiEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Quan-Lin LiEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. li.quanlin@zs-hospital.sh.cn.
Ping-Hong ZhouEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. zhou.pinghong@zs-hospital.sh.cn.ORCID http://orcid.org/0000-0002-5434-0540

Funding

the National Natural Science Foundation of China 82000507the National Natural Science Foundation of China 82170555the National Natural Science Foundation of China 82270569
6 · The paper itself

Abstract

BACKGROUND AND

aimsAlthough endoscopic resection is widely accepted for pyloric lesions, endoscopic submucosal dissection (ESD) of pyloric neoplasms remains technically challenging. The study aimed to assess the efficacy and safety of ESD for pyloric neoplasms.

methodsFrom June 2011 to August 2024, we retrospectively analyzed 103 patients with pyloric neoplasms who underwent ESD at the Endoscopy Center of Zhongshan Hospital. Clinical data,‌ including patient demographics, procedural outcomes, and follow-up results, were collected.

resultsAmong 103 lesions, there were 36 prepyloric neoplasms, 49 pyloric neoplasms and 18 postpyloric neoplasms. The median lesion size was 31 mm (range 10-85 mm). The postpyloric group showed longer procedure duration (32 min vs. 39 min vs. 46 min, P = 0.029) and lower rate of en bloc resection (100.0% vs. 95.9% vs. 83.3%, P = 0.026) compared with the prepyloric group and pyloric group. No patients required conversion to open surgery. After procedure, delayed bleeding occurred in ‌one patient each‌ from the prepyloric and pyloric groups. During a median follow-up of 25 months (range: 6-81 months), only ‌one recurrence‌ (pyloric group) was observed. Post-ESD pyloric stenosis developed in 5 patients, all of whom achieved ‌symptomatic relief‌ through endoscopic balloon dilation (EBD) without complications.

conclusionsESD is a feasible and safe treatment for pyloric neoplasms. Additionally, EBD appears to be a safe and effective ‌therapeutic approach for post-ESD pyloric stenosis.

Indexed as

Endoscopic Mucosal ResectionGastroscopyPylorusStomach NeoplasmsAdultAgedAged, 80 and overFemaleFollow-Up StudiesGastric MucosaHumansMaleMiddle AgedOperative TimeRetrospective StudiesTreatment OutcomeEndoscopic balloon dilationEndoscopic submucosal dissectionPyloric neoplasmsPyloric stenosis

Identifiers

PMID40957971

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.