Evidence map›Paper›PMID 40957958›Full record

ArticlePediatric surgery international2025

Clinical characteristics and outcomes of anterior anus in female infants: a multicenter retrospective cohort study.

Yong Jae Kwon, Hyunhee Kwon, Suhyeon Ha, Dae Yeon Kim, Yu Jeong Cho, Ju Yeon Lee, So Hyun Nam, Eunyoung Jung

Abstract readMulticenter Study
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In one paragraph

Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yong Jae KwonGangNeung Asan Hospital, University of Ulsan College of Medicine, GangNeung, Republic of Korea.
Hyunhee KwonAsan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Suhyeon HaAsan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Dae Yeon KimAsan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Yu Jeong ChoHanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea.
Ju Yeon LeeChonnam National University Hospital, Gwangju, Republic of Korea.
So Hyun NamInje University Busan Paik Hospital, Busan, Republic of Korea.
Eunyoung JungDepartment of Pediatric Surgery, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, 1035 Dalgubeol-Daero, Dalseo-Gu, Daegu, 42601, Republic of Korea. eyjung@kmu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnterior anus (AA) is a congenital anatomical variant with unclear clinical implications and management strategies. This study evaluated the clinical features, associated anomalies, and outcomes of AA in female infants.

methodsThis multicenter retrospective cohort study included infants diagnosed with AA between 2020 and 2024 at six tertiary referral centers in South Korea. The clinical characteristics, coexisting anomalies, and outcomes including constipation and urinary tract infections were analyzed.

resultsAmong the 64 patients included in this study, 51.6% had a concomitant perineal groove. Congenital heart diseases were the most common coexisting anomaly, occurring in 32 patients. During a mean follow-up of 22.9 months, constipation was observed in 23% of the patients. Urinary tract infections were not observed. The perineal groove resolved spontaneously in 87.9% of cases.

conclusionAA is a benign anatomical variant that does not increase the risk of constipation or urinary tract infections. Given the observed association with congenital heart disease, cardiac evaluation should be considered when clinically indicated.

Indexed as

Anal CanalAnorectal MalformationsCohort StudiesConstipationFemaleHumansInfantInfant, NewbornRepublic of KoreaRetrospective StudiesUrinary Tract InfectionsAnorectal malformationAnterior anusConstipationInfantsPerineal grooveUrinary tract infection

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