Evidence map›Paper›PMID 40957935›Full record

ArticleInsights into imaging2025

Understanding different aspects of blood supply of uterine fibroids: an overview of ultrasound and magnetic resonance imaging techniques.

Derk Jan Slotman, Marissa Frijlingh, L J M Juffermans, L W Bartels, C T W Moonen, T Bosch van den, M F Boomsma, J A F Huirne

Abstract read
In one paragraph

Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Derk Jan Slotman *Department of Radiology, Isala, Zwolle, The Netherlands. d.j.slotman@isala.nl.ORCID http://orcid.org/0000-0002-3358-1986
Marissa Frijlingh *Department of Obstetrics and Gynecology, Amsterdam UMC, Amsterdam, The Netherlands.
L J M JuffermansDepartment of Obstetrics and Gynecology, Amsterdam UMC, Amsterdam, The Netherlands.
L W BartelsImage Sciences Institute, Imaging & Oncology Division, University Medical Center Utrecht, Utrecht, The Netherlands.
C T W MoonenImage Sciences Institute, Imaging & Oncology Division, University Medical Center Utrecht, Utrecht, The Netherlands.
T Bosch van denDepartment of Obstetrics and Gynecology, University Hospital Leuven, Leuven, Belgium.
M F BoomsmaDepartment of Radiology, Isala, Zwolle, The Netherlands.
J A F HuirneDepartment of Obstetrics and Gynecology, Amsterdam UMC, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVasculature and blood flow play a crucial role in the genesis, diagnosis, and treatment of uterine fibroids. Assessment of the different aspects of blood flow by medical imaging has therefore gained a prominent place in the clinical management and research of uterine fibroids. Imaging is most often performed with ultrasound and MRI. However, consistent terminology describing the blood flow and vasculature of fibroids is lacking, impeding efficient interdisciplinary communication. PURPOSE: This narrative review provides information on blood flow and vasculature in uterine fibroids and offers insights into ultrasound and MRI techniques for measuring and visualizing these physiological parameters. To contribute to consistent terminology, we propose a generic nomenclature for different aspects of blood flow and vasculature. DISCUSSION: Fibroids generally have a complex and variable vascular composition, which can be unraveled for a large part with the wide range of currently available ultrasound and MRI techniques. Future studies focusing on uterine fibroids may benefit from the connections laid in this article between fibroid vasculature, qualitative and quantitative ultrasound and MRI techniques and our proposed nomenclature. CRITICAL RELEVANCE STATEMENT: This review aims to contribute to a deeper understanding of the blood supply of uterine fibroids and the available imaging techniques for its visualization. This may lead to improved clinical management of uterine fibroids and more efficient interdisciplinary communication. KEY POINTS: Blood supply is crucial in the genesis, diagnosis, and treatment of fibroids. Ultrasound and MRI can unravel the complex vascular composition of fibroids. Consistent nomenclature around blood supply can improve clinical management of fibroids.

Indexed as

Blood circulationMedical imagingRegional blood flowUterine fibroid

Identifiers

PMID40957935
PMCPMC12440848

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.