Evidence map›Paper›PMID 40957914›Full record

ArticleClinical oral investigations2025

Numerical simulation and functional evaluation of upper airway before and after twin block treatment with different respiratory pathways.

Shuai Chen, Yu Han, Jingying Wang, Xue Song

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Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Shuai ChenDepartment of Stomatology, Jinan Central Hospital, Jinan, Shandong Province, China.
Yu HanDepartment of Stomatology, Jinan Central Hospital, Jinan, Shandong Province, China.
Jingying WangSchool of Nuclear Science, Energy and Power Engineering, Shandong University, Jinan, Shandong Province, China.
Xue SongDepartment of Ultrasonography, Jinan Central Hospital, Jinan, Shandong Province, China. songxue_sdu@mail.sdu.edu.cn.

Funding

Natural Science Foundation of Shandong Province ZR2024QH327Start-up fund for the introduction of talents to Jinan Central Hospital YJ0063
6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the changes of upper airway ventilation function in children with mandible retrognathia under different respiratory pathways after Twin Block (TB) using computational fluid dynamics (CFD). MATERIALS AND

methodsThis study included 20 patients with mandible retrognathia who underwent TB treatment, including 8 males and 12 females (age 10.67 ± 1.51 years). The airflow information obtained by using an oral and nasal thermistor was used as the boundary condition for CFD simulation to analyze the influence of different respiratory paths on upper airway flow.

resultsAfter TB, the pressure drop, resistance, and shear force in the velopharynx (Vp) and glossopharynx (Gp) were significantly reduced during nasal breathing. Pearson correlation test showed that obstructive apnea index (OAI) was negatively correlated with the internal pressure of the upper airway, and positively correlated with the pressure drop, resistance, and maximum shear force of the upper airway, especially the velopharynx resistance, which showed a significant positive correlation. For patients with obvious oral breathing, the improvement of fluid dynamics parameters inside the glossopharyngeal region was more significant. The OAI was significantly positively correlated with the pressure drop and resistance in the glossopharynx region.

conclusionsFor different respiratory pathways, TB can improve the ventilation function of patients with mandible retrognathia.

Indexed as

RetrognathiaChildComputer SimulationFemaleHumansHydrodynamicsMaleAirwayCollapseComputational fluid dynamicsMandible retrognathiaTwin block

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.