Evidence map›Paper›PMID 40957898›Full record

ArticleInternational journal of obesity (2005)2025

Abdominal skeletal muscle quality and quantity are independently and jointly associated with cardiometabolic health in children.

Emiliano Miranda-Ferrua, Cristina Cadenas-Sanchez, María Medrano, Jonatan R Ruiz, Fernando Idoate, Maddi Osés, Mara Concepción, Rafael Cabeza, Idoia Labayen

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Article in International journal of obesity (2005), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emiliano Miranda-Ferrua *Department of Health Sciences, Institute for Sustainability & Food Chain Innovation (IS-FOOD), Public University of Navarra, Pamplona, Spain.
Cristina Cadenas-Sanchez *CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Granada, Spain.
María MedranoDepartment of Health Sciences, Institute for Sustainability & Food Chain Innovation (IS-FOOD), Public University of Navarra, Pamplona, Spain.
Jonatan R RuizCIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Granada, Spain.ORCID 0000-0002-7548-7138
Fernando IdoateRadiology Department, Mutua Navarra, Department of Health Sciences, Public University of Navarra, Pamplona, Spain.
Maddi OsésDepartment of Health Sciences, Institute for Sustainability & Food Chain Innovation (IS-FOOD), Public University of Navarra, Pamplona, Spain.
Mara ConcepciónDepartment of Health Sciences, Institute for Sustainability & Food Chain Innovation (IS-FOOD), Public University of Navarra, Pamplona, Spain.
Rafael CabezaDepartment of Electrical, Electronic and Communications Engineering, Public, University of Navarra, Pamplona, Spain.
Idoia LabayenDepartment of Health Sciences, Institute for Sustainability & Food Chain Innovation (IS-FOOD), Public University of Navarra, Pamplona, Spain. idoia.labayen@unavarra.es.ORCID 0000-0002-4334-3287

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the independent and joint associations between intermuscular abdominal adipose tissue and abdominal skeletal muscle tissue with cardiometabolic health indicators in children.

methodsThis cross-sectional study included 114 children (10.6 ± 1.1 y, 54% girls) and 56 children (11.3 ± 1.5 y, 39% girls) from two cohorts. Total abdominal area (TAA), intermuscular abdominal adipose tissue (IMAAT) and abdominal skeletal muscular tissue (AMT) were measured by magnetic resonance imaging. Cardiometabolic health was evaluated by triglycerides-to-HDL ratio (TG/HDL), mean arterial pressure (MAP), HOMA-IR and metabolic syndrome z-score (MetSynd).

resultsIMAAT was associated with higher MetSynd regardless of total adiposity in both cohorts (P < 0.05). In the EFIGRO project, the associations of IMAAT with HOMA-IR and TG/HDL ratio were independent of total adiposity (P < 0.05). The relationship of IMAAT with MAP was attenuated after controlling for total adiposity in both cohorts (P < 0.09). The AMT/TAA ratio was inversely associated with the TG/HDL ratio, MAP, HOMA-IR, and MetSynd in both cohorts (P < 0.01). Joint associations showed that children with high IMAAT and low AMT/TAA ratio had significantly higher HOMA-IR (P < 0.01) and MetSynd (P < 0.05) than those with low IMAAT and high AMT/TAA ratio in both cohorts.

conclusionsBoth high IMAAT and low AMT are associated to poor cardiometabolic health already in childhood.

Indexed as

Abdominal FatAbdominal MusclesMetabolic SyndromeAdiposityCardiometabolic Risk FactorsChildCross-Sectional StudiesFemaleHumansMagnetic Resonance ImagingMale

Identifiers

PMID40957898

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.