Evidence map›Paper›PMID 40957420›Full record

ArticleImmunity2025

Integrin CD103 expression in naive CD8

Can Li, Davinna L Ligons, Dominic Lanasa, Hilary R Keller, Megan A Luckey, Brian Capaldo, Daoud Meerzaman, Joo-Young Park, Jung-Hyun Park

Abstract read
In one paragraph

Article in Immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Origins of CD8 tissue resident memory.Frontiers in immunology · 2026
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Can LiExperimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Davinna L LigonsExperimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Dominic LanasaExperimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Hilary R KellerExperimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Department of Surgery, Guthrie Robert Packer Hospital, Sayre, PA 18840, USA.
Megan A LuckeyExperimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Brian CapaldoCenter for Biomedical Informatics and Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Daoud MeerzamanCenter for Biomedical Informatics and Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Joo-Young ParkExperimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Department of Oral and Maxillofacial Surgery, Seoul National University School of Dentistry, 101 Daehakno, Jongno-gu, Seoul 03080, South Korea.
Jung-Hyun ParkExperimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: parkhy@mail.nih.gov.

Funding

Post-Transcriptional Regulation of Interleukin-7 Receptor ExpressionZIABC011214 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PARK, JUNG-HYUN · 2009 to 2025
$15.9M
Immune Regulatory Roles of Suppressor Of Cytokine Signaling (SOCS) MoleculesZIABC011215 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PARK, JUNG-HYUN · 2009 to 2025
$6.9M
Intramural NIH HHS Z99 CA999999Intramural NIH HHS ZIA BC011214Intramural NIH HHS ZIA BC011215
6 · The paper itself

Abstract

Integrin CD103 binds to E-cadherin, a cell adhesion molecule predominantly expressed on epithelial cells, thus mediating the tissue residency of CD103

Indexed as

Antigens, CDCD8-Positive T-LymphocytesImmunologic MemoryIntegrin alpha ChainsAnimalsCadherinsCell DifferentiationCytokinesDendritic CellsInterleukin-12Lymphocyte ActivationMemory T CellsMiceMice, Inbred C57BLMice, KnockoutPhenotypealpha E integrinsAntigens, CDCadherinsCytokinesIntegrin alpha ChainsInterleukin-12dendritic cellsE-cadherinIFN-βIL-12IL-15

Identifiers

PMID40957420
PMCPMC12441315

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.