Evidence map›Paper›PMID 40956884›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

How palytoxin transforms the Na

Ryuta Kanai, Naoki Tsunekawa, Flemming Cornelius, Bente Vilsen, Chikashi Toyoshima

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryuta KanaiInstitute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku 113-0032, Tokyo, Japan.ORCID 0000-0002-9213-5193
Naoki TsunekawaInstitute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku 113-0032, Tokyo, Japan.
Flemming CorneliusDepartment of Biomedicine, Aarhus University, Aarhus C 8000, Denmark.ORCID 0000-0003-1566-0020
Bente VilsenDepartment of Biomedicine, Aarhus University, Aarhus C 8000, Denmark.ORCID 0000-0002-4727-9382
Chikashi ToyoshimaInstitute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku 113-0032, Tokyo, Japan.ORCID 0000-0001-9640-0778

Funding

Lundbeck Foundation (Lundbeckfonden) R223-2016-595MEXT | Japan Society for the Promotion of Science (JSPS) 23H02443MEXT | Japan Society for the Promotion of Science (JSPS) JP19H00975MEXT | Japan Society for the Promotion of Science (JSPS) JP21K06109MEXT | Japan Society for the Promotion of Science (JSPS) JP24K01985Novo Nordisk Fonden (NNF) NNF13OC0006555Novo Nordisk Fonden (NNF) NNF14OC0013409Takeda Science Foundation (TSF) 2022020235The Danish Council for Independent Research DFF4183-00011AThe Danish Council for Independent Research DFF 7016-00193B
6 · The paper itself

Abstract

Palytoxin (PTX), a potent marine toxin, has long been known to transform Na

Indexed as

AcrylamidesCnidarian VenomsSodium-Potassium-Exchanging ATPaseAnimalsCationsIon Channel GatingPolyether ToxinsSodiumAcrylamidesCationsCnidarian VenomspalytoxinPolyether ToxinsSodiumSodium-Potassium-Exchanging ATPasecryoelectron microscopygatingion pumpNa+,K+-ATPasepalytoxin

Identifiers

PMID40956884
PMCPMC12478176

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.