ReviewDeutsches Arzteblatt international2025
Clinical Recommendations for the Acute Care of Patients With Traumatic Spinal Cord Injury.
Review in Deutsches Arzteblatt international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Dysregulation of CD36 and CPT1A is associated with fatty acid metabolic disorder and cardiomyocyte injury after high-cervical spinal cord injury.Molecular and cellular biochemistry · 2026Article
- Severe trauma care: advances and future directions in diagnostic and therapeutic techniques and information technology support.Medical review (2021) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute traumatic spinal cord injury (tSCI) is among the more complex challenges in modern medicine and has far-reaching implications for the affected patients' quality of life. A practical summary for treating physicians of the currently recommended clinical measures for the acute care of patients with tSCI is needed as an evidence-based guide to treatment.
methodsThis narrative review is based on pertinent publications (1984-2024) retrieved by a search in the PubMed, Cochrane, and EMBASE databases, with particular attention to the updated clinical practice guideline on acute spinal cord trauma issued by AO Spine in 2024. The abstracts were examined for relevance, and the full text of selected articles was studied.
resultsThe evidence base for the management of tSCI includes only a small number of randomized controlled trials. As a result, the evidence underlying many of the recommendations is on a moderate or low level. Early surgical decompression (within 24 hours) is associated with a significantly better neurological outcome: it more than doubles the likelihood of an improvement of ≥ 2 points on the ASIA Impairment Scale (AIS) (RR: 2.76, 95% confidence interval [1,60; 4,98]; moderate evidence level). Maintaining an adequate mean arterial blood pressure is considered to be essential, despite the absence of robust evidence for any specific protocol (very low evidence level). The use of corticosteroids remains controversial because of conflicting evidence.
conclusionThe treatment of tSCI requires a multidisciplinary, evidence-based approach including early surgery and patient-oriented hemodynamic management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.